Conduction Abnormalities Following Combined Surgical and Transcatheter Approaches for Severe Aortic Stenosis and Coronary Artery Disease - Scorecard - MDSpire

Conduction Abnormalities Following Combined Surgical and Transcatheter Approaches for Severe Aortic Stenosis and Coronary Artery Disease

  • By

  • Zulfugar T. Taghiyev

  • Emrah C. Karabacak

  • Martin V. Fuchs

  • Katharina E. Jaeger

  • Balli Chapugi

  • Oliver Dörr

  • Peter Roth

  • Andreas Böning

  • February 13, 2026

  • 0 min

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Clinical Scorecard: Conduction Abnormalities Following Combined Surgical and Transcatheter Approaches for Severe Aortic Stenosis and Coronary Artery Disease

At a Glance

CategoryDetail
ConditionSevere Aortic Stenosis with Coronary Artery Disease
Key MechanismsIncreased incidence of conduction disturbances and need for permanent pacemaker implantation following TAVR and SAVR due to anatomical proximity of conduction pathways.
Target PopulationPatients with severe aortic stenosis and concomitant coronary artery disease.
Care SettingCardiovascular surgical and interventional settings.

Key Highlights

  • TAVR is increasingly used for patients with lower surgical risk.
  • Conduction abnormalities post-intervention can lead to permanent pacemaker implantation.
  • Reported rates of PPI following TAVR range from 3.4% to 25.9%.
  • High-grade atrioventricular block is a common reason for pacing therapy.
  • The SYNTAX I score is used to assess coronary artery disease complexity.

Guideline-Based Recommendations

Diagnosis

  • Assess severity of aortic stenosis using valve area and transvalvular gradient.

Management

  • Consider TAVR + PCI or SAVR + CABG based on patient-specific factors.

Monitoring & Follow-up

  • Monitor for conduction disturbances post-intervention.

Risks

  • Evaluate risks of high-grade atrioventricular block and need for PPI.

Patient & Prescribing Data

Patients with severe aortic stenosis and verified coronary artery disease.

Treatment decisions should be made by a multidisciplinary heart team.

Clinical Best Practices

  • Utilize propensity score matching to minimize selection bias in treatment comparisons.
  • Perform comprehensive preoperative assessments including SYNTAX I score.

References

Original Source(s)

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