Systematic Review of Postoperative Periprosthetic Fractures Linked to Compressive Osseointegration with the Zimmer Biomet Compress® Device

Category	Detail
Condition	Postoperative Periprosthetic Fractures
Key Mechanisms	Compressive osseointegration via the Zimmer Biomet Compress® device promotes bone hypertrophy but increases fracture risk.
Target Population	Patients undergoing massive endoprosthetic reconstruction for oncological or traumatic indications.
Care Setting	Surgical and postoperative care for limb salvage procedures.

Periprosthetic fractures associated with the CPS device are uncommon, with an overall incidence of 2.7%.
Fractures predominantly occur within the first 2 postoperative years.
The CPS device's failure profile differs from traditional cemented stems, which fail due to late-onset aseptic loosening.
Methodological quality of included studies was moderate, with common weaknesses noted.
Comparative analysis with cemented stems requires caution due to differences in study designs.

Consider the unique failure profile of the CPS device when planning surgical interventions.

Regular follow-up assessments to evaluate osseointegration and detect early signs of fracture.

Increased risk of periprosthetic fractures at the bone-implant interface due to high compressive forces.

Patients receiving the CPS device for limb salvage after oncological resection or complex trauma.

Low absolute fracture rates suggest the CPS device may be a viable alternative to traditional cemented implants.

Utilize comprehensive preoperative planning to assess patient suitability for the CPS device.
Educate patients on the potential risks and benefits associated with the CPS device.

Clinical Scorecard: Systematic Review of Postoperative Periprosthetic Fractures Linked to Compressive Osseointegration with the Zimmer Biomet Compress® Device