Early neural shift detection using functional magnetic resonance imaging: a pilot study with Parkinson’s disease patients undergoing istradefylline and hybrid assistive limb interventions - Scorecard - MDSpire

Early neural shift detection using functional magnetic resonance imaging: a pilot study with Parkinson’s disease patients undergoing istradefylline and hybrid assistive limb interventions

  • By

  • Ken-ichi Tabei

  • Keita Matsuura

  • Naoko Nakamura

  • Hiroyuki Kajikawa

  • Hidekazu Tomimoto

  • Akihiro Shindo

  • May 15, 2026

  • 0 min

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Clinical Scorecard: Detection of Early Neural Shifts via Functional Magnetic Resonance Imaging: A Preliminary Investigation in Parkinson’s Disease Patients Receiving Istradefylline and Hybrid Assistive Limb Therapy

At a Glance

CategoryDetail
Condition
Key MechanismsIstradefylline as an adenosine A2A receptor antagonist; Hybrid Assistive Limb (HAL) for motor enhancement. Clarify the specific neural pathways affected.
Target Population
Care Setting

Key Highlights

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Guideline-Based Recommendations

Diagnosis

    Management

      Monitoring & Follow-up

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      Risks

        Patient & Prescribing Data

        Include details on the duration and dosage of istradefylline therapy.

        Clinical Best Practices

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        Related Resources & Content

        Original Source(s)

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