Evaluation of Choroidal Thickness and Vascularity Following Corneal Crosslinking in Patients with Keratoconus
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By
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Hasan Kızıltoprak
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Burak Ören
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Dilara Ozkoyuncu Kocabas
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Kemal Tekin
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February 12, 2026
Clinical Scorecard: Evaluation of Choroidal Thickness and Vascularity Following Corneal Crosslinking in Patients with Keratoconus
At a Glance
| Category | Detail |
|---|
| Condition | Keratoconus |
| Key Mechanisms | Corneal collagen cross-linking (CXL) using riboflavin and UVA radiation to stabilize corneal ectatic disorders. |
| Target Population | Patients with progressive keratoconus, particularly young individuals. |
| Care Setting | Ophthalmology department in a university hospital. |
Key Highlights
- CXL effectively improves corneal strength and reduces irregular astigmatism.
- Choroidal thickness (CT) and choroidal vascular index (CVI) were evaluated post-CXL.
- No significant complications reported during or after CXL procedures.
Guideline-Based Recommendations
Diagnosis
- Clinical and topographic diagnosis of keratoconus.
- Use of SD-OCT for structural evaluation.
Management
- Accelerated CXL method with riboflavin and UVA irradiation.
- Post-operative care includes antibiotic and anti-inflammatory drops.
Monitoring & Follow-up
- Regular ophthalmological examinations including visual acuity and intraocular pressure.
Risks
- Potential corneal complications such as haze, infections, and endothelial damage.
Patient & Prescribing Data
Patients with progressive keratoconus and specific inclusion criteria.
Topical moxifloxacin and loteprednol prescribed post-CXL.
Clinical Best Practices
- Ensure high-quality SD-OCT scans for accurate measurement.
- Monitor systemic blood pressure before procedures.
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