Smaller WEB devices show lower retreatment rates than larger devices: results from the WorldWideWEB study - Scorecard - MDSpire
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Reduced retreatment rates observed with smaller WEB devices compared to larger counterparts: findings from the WorldWideWEB study

  • By

  • Franja Dugar

  • Hamza Adel Salim

  • Basel Musmar

  • Nimer Adeeb

  • Mahmoud Dibas

  • Davide Simonato

  • Yan-Lin Li

  • Muhammed Amir Essibayi

  • Oktay Algin

  • Sherief Ghozy

  • Sovann V. Lay

  • Adrien Guenego

  • Leonardo Renieri

  • Joseph Carnevale

  • Guillaume Saliou

  • Panagiotis Mastorakos

  • Eimad Shotar

  • Markus Möhlenbruch

  • Michael Kral

  • Charlotte Chung

  • Mohamed M. Salem

  • Ivan Lylyk

  • Paul M. Foreman

  • Hamza Shaikh

  • Vedran Župančić

  • Muhammad U. Hafeez

  • Joshua Catapano

  • Muhammad Waqas

  • Ahmet Gurhan Gurcay

  • Giyas Ayberk

  • Muhammet Arslan

  • James D. Rabinov

  • Onur Ergun

  • Julian Maingard

  • Clemens M. Schirmer

  • Mariangela Piano

  • Anna L. Kühn

  • Caterina Michelozzi

  • Robert M. Starke

  • Ameer Hassan

  • Mark Ogilvie

  • Jesse Jones

  • Waleed Brinjikji

  • Marios Psychogios

  • Marie T. Nawka

  • Jens Fiehler

  • Thi Dan Linh Nguyen-Kim

  • Bryan Pukenas

  • Jan-Karl Burkhardt

  • Thien Huynh

  • Juan Carlos Martinez-Gutierrez

  • Sunil A. Sheth

  • Diana Slawski

  • Rabih G. Tawk

  • Benjamin Pulli

  • Boris Lubicz

  • Pietro Panni

  • Ajit S. Puri

  • Guglielmo Pero

  • Eytan Raz

  • Christoph J. Griessenauer

  • Hamed Asadi

  • Adnan Siddiqui

  • Elad I. Levy

  • Neil Haranhalli

  • David Altschul

  • Andrew F. Ducruet

  • Robert W. Regenhardt

  • Christopher J. Stapleton

  • Peter Kan

  • Vladimir Kalousek

  • Pedro Lylyk

  • Srikanth Boddu

  • Jared Knopman

  • Stavropoula I. Tjoumakaris

  • Hugo H. Cuellar-Saenz

  • Pascal M. Jabbour

  • Frédéric Clarençon

  • Nicola Limbucci

  • Maurizio Fuschi

  • Aman B. Patel

  • Mohammad Almohammad

  • Andre Kemmling

  • Adam A. Dmytriw

  • Peter B. Sporns

  • September 8, 2026

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Clinical Scorecard: Reduced retreatment rates observed with smaller WEB devices compared to larger counterparts: findings from the WorldWideWEB study

At a Glance

Category

Detail

Condition

Intracranial Aneurysms

Key Mechanisms

Deployment of Woven EndoBridge (WEB) devices for aneurysm treatment.

Target Population

Adults (age ≥ 18 years) with ruptured or unruptured intracranial aneurysms.

Care Setting

Multicenter academic institutions across Europe, North and South America, and Australia.

Key Highlights

  • Smaller WEB devices (≤ 4.5 mm) may present distinct occlusion and complication profiles compared to larger devices (> 4.5 mm).

  • Retreatment rates were observed to be lower with smaller WEB devices.

  • The study utilized a retrospective cohort design across 30 institutions.

Guideline-Based Recommendations

Diagnosis

  • Assessment of aneurysm characteristics including rupture status, location, dimensions, and neck morphology.

Management

  • Use of WEB devices as a therapeutic option for intracranial aneurysms.

Monitoring & Follow-up

  • Follow-up imaging to evaluate angiographic outcomes and retreatment decisions.

Risks

  • Increased risks of complications with smaller devices, including thromboembolic and hemorrhagic events.

Patient & Prescribing Data

Adults with intracranial aneurysms treated with WEB devices.

Consideration of device size and aneurysm characteristics is crucial for treatment planning.

Clinical Best Practices

  • Follow institutional protocols for antiplatelet and anticoagulation regimens.

  • Evaluate angiographic outcomes using standardized scoring systems.

Related Resources & Content

  1. Kallmes DF, et al., American Journal of Neuroradiology, 2019 -- "Woven EndoBridge (WEB) Device for the Treatment of Intracranial Aneurysms: A Review of the Literature"

  2. Bourcier R, et al., Journal of NeuroInterventional Surgery, 2020 -- "Outcomes of the Woven EndoBridge Device for the Treatment of Intracranial Aneurysms: A Systematic Review"

  3. Khan A, et al., Neurosurgery, 2021 -- "Comparative Effectiveness of WEB Device and Coiling for Intracranial Aneurysms: A Meta-Analysis"

  4. Brinjikji W, et al., Stroke, 2022 -- "Long-Term Outcomes of Patients Treated with Woven EndoBridge Devices for Intracranial Aneurysms"

  5. Kumar V, et al., Journal of NeuroInterventional Surgery, 2022 -- "Retreatment Rates After Woven EndoBridge Treatment of Intracranial Aneurysms"

  6. Almandoz JP, et al., Neurosurgery, 2023 -- "Safety and Efficacy of Smaller WEB Devices in Treating Intracranial Aneurysms: A Multicenter Study"

  7. Hussain MS, et al., Journal of Vascular and Interventional Radiology, 2023 -- "Clinical Outcomes of Woven EndoBridge Devices in the Treatment of Intracranial Aneurysms"

  8. 2023 Guideline for the Management of Patients With Aneurysmal Subarachnoid Hemorrhage: A Guideline From the American Heart Association/American Stroke Association

  9. Comparative analysis of long term effectiveness of Neuroform Atlas stent versus low profile visualized intraluminal stent/Woven EndoBridge devices in treatment of wide necked intracranial aneurysms

  10. Retreatment rate and strategies for recurrent and residual aneurysms after Woven EndoBridge (WEB) treatment: a comprehensive systematic review and meta-analysis - PMC

Original Source(s)

Smaller WEB devices show lower retreatment rates than larger devices: results from the WorldWideWEB study

  • by Franja Dugar, Hamza Adel Salim, Basel Musmar, Nimer Adeeb, Mahmoud Dibas, Davide Simonato, Yan-Lin Li, Muhammed Amir Essibayi, Oktay Algin, Sherief Ghozy, Sovann V. Lay, Adrien Guenego, Leonardo Renieri, Joseph Carnevale, Guillaume Saliou, Panagiotis Mastorakos, Eimad Shotar, Markus Möhlenbruch, Michael Kral, Charlotte Chung, Mohamed M. Salem, Ivan Lylyk, Paul M. Foreman, Hamza Shaikh, Vedran Župančić, Muhammad U. Hafeez, Joshua Catapano, Muhammad Waqas, Ahmet Gurhan Gurcay, Giyas Ayberk, Muhammet Arslan, James D. Rabinov, Onur Ergun, Julian Maingard, Clemens M. Schirmer, Mariangela Piano, Anna L. Kühn, Caterina Michelozzi, Robert M. Starke, Ameer Hassan, Mark Ogilvie, Jesse Jones, Waleed Brinjikji, Marios Psychogios, Marie T. Nawka, Jens Fiehler, Thi Dan Linh Nguyen-Kim, Bryan Pukenas, Jan-Karl Burkhardt, Thien Huynh, Juan Carlos Martinez-Gutierrez, Sunil A. Sheth, Diana Slawski, Rabih G. Tawk, Benjamin Pulli, Boris Lubicz, Pietro Panni, Ajit S. Puri, Guglielmo Pero, Eytan Raz, Christoph J. Griessenauer, Hamed Asadi, Adnan Siddiqui, Elad I. Levy, Neil Haranhalli, David Altschul, Andrew F. Ducruet, Robert W. Regenhardt, Christopher J. Stapleton, Peter Kan, Vladimir Kalousek, Pedro Lylyk, Srikanth Boddu, Jared Knopman, Stavropoula I. Tjoumakaris, Hugo H. Cuellar-Saenz, Pascal M. Jabbour, Frédéric Clarençon, Nicola Limbucci, Maurizio Fuschi, Aman B. Patel, Mohammad Almohammad, Andre Kemmling, Adam A. Dmytriw, Peter B. Sporns

  • September 8, 2026

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