Association between triglyceride-glucose body mass index and risk of hypertensive disorders of pregnancy: a case-control study - Scorecard - MDSpire

Association between triglyceride-glucose body mass index and risk of hypertensive disorders of pregnancy: a case-control study

  • By

  • Jun Liu

  • Haoran Ma

  • Xi Chen

  • Xueyun Chang

  • June 25, 2026

  • 0 min

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Clinical Scorecard: Link Between Triglyceride-Glucose Body Mass Index and Hypertensive Disorders in Pregnancy: A Case-Control Analysis

At a Glance

CategoryDetail
ConditionHypertensive Disorders of Pregnancy (HDP)
Key MechanismsInsulin resistance and obesity are core metabolic dimensions in HDP pathogenesis.
Target PopulationPregnant women hospitalized for hypertensive disorders.
Care SettingDepartment of Obstetrics at Fuyang Women and Children's Hospital

Key Highlights

  • TyG-BMI is significantly higher in HDP patients compared to controls.
  • Each 10-unit increase in TyG-BMI is associated with a 30% increase in HDP risk.
  • TyG-BMI shows superior discriminative performance for HDP compared to TyG index and BMI.

Guideline-Based Recommendations

Diagnosis

  • Use TyG-BMI as a comprehensive indicator for identifying metabolic abnormalities in HDP.

Management

    Monitoring & Follow-up

      Risks

      • HDP is associated with increased risks of maternal mortality, perinatal mortality, preterm birth, and long-term cardiovascular disease.

      Patient & Prescribing Data

      Pregnant women with hypertensive disorders.

      Assessment of TyG-BMI can aid in identifying patients at risk for HDP.

      Clinical Best Practices

      • Consider TyG-BMI for risk assessment in pregnant women.
      • Monitor metabolic parameters in patients with HDP.

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