High-flow nasal oxygen in perioperative and critical care: a bibliometric analysis
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By
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Biao Xi
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Yuting Zhao
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Wei Fu
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Yunzhi Ling
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Qin Zhuang
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Di Zhang
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July 15, 2026
Clinical Scorecard: Bibliometric Assessment of High-Flow Nasal Oxygen Utilization in Perioperative and Critical Care Settings
At a Glance
| Category | Detail |
|---|
| Condition | High-Flow Nasal Oxygen Utilization |
| Key Mechanisms | Noninvasive respiratory support strategy delivering heated and humidified gas at high flow rates. |
| Target Population | Adults in perioperative and critical care settings. |
| Care Setting | Perioperative and critical care practice. |
Key Highlights
- HFNO research has shown sustained exponential growth, particularly after 2018.
- The literature is concentrated in respiratory medicine, critical care, and anesthesiology.
- Major clusters identified include acute respiratory failure and perioperative oxygen therapy.
- Current research focuses on context-specific use, monitoring, and failure prediction.
- The ROX index has been evaluated as a predictor of HFNO success.
Guideline-Based Recommendations
Diagnosis
- HFNO is recognized as an important option for selected patients with acute respiratory failure.
Management
- HFNO is widely applied in acute hypoxemic respiratory failure and treatment stabilization.
Monitoring & Follow-up
- Monitoring treatment response and the need for escalation is crucial in HFNO application.
Risks
- Identifying patients most likely to benefit and recognizing early treatment failure is essential.
Patient & Prescribing Data
Adults with acute hypoxemic respiratory failure in perioperative and critical care settings.
HFNO has applications in preoxygenation, apneic oxygenation, and sedation support.
Clinical Best Practices
- Utilize HFNO for oxygenation support during airway management.
- Implement the ROX index for predicting HFNO success.
- Prioritize clinically actionable patient stratification and standardized outcome definitions.
Related Resources & Content
