Global Trends and Research Topics in Gastric Bypass Clinical Trials: A Bibliometric Analysis and Latent Dirichlet Allocation (LDA) Study - Scorecard - MDSpire
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Global Trends and Research Topics in Gastric Bypass Clinical Trials: A Bibliometric Analysis and Latent Dirichlet Allocation (LDA) Study
Clinical Scorecard: Analysis of Global Patterns and Research Focus in Gastric Bypass Clinical Trials: A Bibliometric and Latent Dirichlet Allocation Study
At a Glance
Category
Detail
Condition
Severe obesity
Key Mechanisms
Gastric restriction, alterations in intestinal transit, hormonal modulation
Target Population
Individuals with severe obesity (BMI ≥ 40 kg/m²)
Care Setting
Clinical trials and metabolic bariatric surgery
Key Highlights
MBS is the reference standard treatment for severe obesity.
Gastric bypass (GB) is one of the oldest and most widely performed MBS procedures.
Patients may achieve up to a 57% reduction in total body weight five years post-surgery.
The number of MBS procedures has increased from 100,092 in 2014 to 598,736 in 2023.
Over 72,000 publications on gastric bypass were retrieved from major databases.
Guideline-Based Recommendations
Diagnosis
Clinical trials should focus on patients undergoing Roux-en-Y gastric bypass.
Management
MBS procedures should be considered for individuals with severe obesity.
Monitoring & Follow-up
Long-term weight loss and metabolic improvement should be assessed post-surgery.
Risks
Potential comorbidities include type 2 diabetes mellitus and hypertension.
Patient & Prescribing Data
Adults with class III obesity (BMI ≥ 40 kg/m²)
MBS, particularly GB, is effective for sustained weight loss and metabolic disease improvement.
Clinical Best Practices
Utilize clinical trials to evaluate the efficacy and safety of gastric bypass.
Adopt evidence-based practices in the implementation of MBS.
