Alterations in urinary metals following pulsed 660 nm photobiomodulation in a pediatric patient with autism spectrum disorder: a case report - Scorecard - MDSpire

Alterations in urinary metals following pulsed 660 nm photobiomodulation in a pediatric patient with autism spectrum disorder: a case report

  • By

  • Alex Zaharakis

  • Christian Bogner

  • June 23, 2026

  • 0 min

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Clinical Scorecard: Changes in Urinary Metal Levels After 660 nm Photobiomodulation in a Child Diagnosed with Autism Spectrum Disorder: A Case Study

At a Glance

CategoryDetail
ConditionAutism Spectrum Disorder (ASD)
Key MechanismsPhotobiomodulation (PBM) modulates mitochondrial cytochrome c oxidase activity and cellular bioenergetics.
Target PopulationChildren diagnosed with Autism Spectrum Disorder.
Care SettingClinical case study.

Key Highlights

  • Increased urinary aluminum levels observed after pulsed 660 nm PBM.
  • Baseline urinary aluminum levels were stable before intervention.
  • Mercury levels exceeded reference values in all specimens.
  • Follow-up showed persistent elevated aluminum levels two months post-PBM.
  • The study highlights the need for controlled studies on PBM effects.

Guideline-Based Recommendations

Diagnosis

  • Monitor urinary metal levels in children with ASD.

Management

  • Consider nonchelation strategies for heavy metal mobilization.

Monitoring & Follow-up

  • Regular follow-up of urinary metal levels post-intervention.

Risks

  • Chelation therapy carries risks including renal toxicity and metal redistribution.

Patient & Prescribing Data

Pediatric patients with Autism Spectrum Disorder.

Pulsed 660 nm PBM may influence urinary metal excretion but requires further investigation.

Clinical Best Practices

  • Document baseline urinary metal levels before any intervention.
  • Use validated methods for urinary metal analysis.
  • Ensure informed consent for case studies and research.

Related Resources & Content

Original Source(s)

Alterations in urinary metals following pulsed 660 nm photobiomodulation in a pediatric patient with autism spectrum disorder: a case report

  • by Alex Zaharakis, Christian Bogner

  • June 23, 2026

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