Adipokine profiles and genetic variants of leptin receptor, adiponectin, and ghrelin pathways in obesity: prospective 12-month outcomes after bariatric interventions - Scorecard - MDSpire

Adipokine profiles and genetic variants of leptin receptor, adiponectin, and ghrelin pathways in obesity: prospective 12-month outcomes after bariatric interventions

  • By

  • Andriy Prodan

  • Ihor Dzyubanovsky

  • Iryna Halabitska

  • Pavlo Petakh

  • Iryna Kamyshna

  • Oleksandr Kamyshnyi

  • May 20, 2026

  • 0 min

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Clinical Scorecard: Genetic Variants and Adipokine Levels in Obesity: A 12-Month Follow-Up Study Post-Bariatric Surgery

At a Glance

CategoryDetail
Condition
Key Mechanisms
Target PopulationAdult patients with varying degrees of obesity undergoing different types of bariatric surgery
Care Setting

Key Highlights

  • Genetic variants significantly influence hormonal changes and weight loss outcomes post-surgery.

Guideline-Based Recommendations

Diagnosis

    Management

      Monitoring & Follow-up

      • Evaluate changes in adipokine levels, BMI, and glycemic control post-surgery.

      Risks

        Patient & Prescribing Data

        Bariatric surgery (including endovascular embolization, gastroplication, or sleeve gastrectomy) effectively normalizes hormonal profiles and improves metabolic outcomes.

        Clinical Best Practices

        • Integrate genetic testing to personalize obesity treatment plans.
        • Monitor hormonal profiles and metabolic parameters post-bariatric surgery, with follow-ups every 3 months for the first year.

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        Original Source(s)

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