Survival Outcomes and Prognostic Indicators in Colorectal Cancer: Findings from a Ghanaian Patient Cohort
By
Tonnies Abeku Buckman
Samuel Asamoah Sakyi
Joseph Yorke
Jonathan Laryea
Bolni Marius Nagalo
Michael Nyantakyi
Emmanuella Nsenbah Batu
Ebenezer Senu
Ernest Osei-Bonsu
Daniel Sam
Emelia Osei Boakye
Francis Acheampong
Francis Agyemang-Yeboah
Christian Obirikorang
Emmanuel Acheampong
December 29, 2025
Clinical Scorecard: Survival Outcomes and Prognostic Indicators in Colorectal Cancer: Findings from a Ghanaian Patient Cohort
At a Glance
Category Detail
Condition Colorectal Cancer (CRC) Key Mechanisms Genetic predisposition, dietary factors, lifestyle choices, and inflammatory bowel disease. Target Population Patients diagnosed with colorectal cancer in Ghana. Care Setting Komfo Anokye Teaching Hospital, Kumasi, Ghana.
Key Highlights
Colorectal cancer is the most commonly diagnosed malignancy in men and the second in women globally. 5-year overall survival rates in sub-Saharan Africa range from 8% to 30%. Limited awareness and socioeconomic barriers contribute to late-stage diagnosis in Ghana. Survival rates decrease drastically from 90% in stage I to 0% in stage IV. The Ghana National Cancer Steering Committee recommends faecal occult blood testing for early detection. Guideline-Based Recommendations
Diagnosis
Utilize faecal occult blood testing for screening. Conduct colonoscopies and imaging for diagnosis. Management
Treatment varies by disease stage, including surgery, chemotherapy, and radiotherapy. Monitoring & Follow-up
Regular follow-up and assessment of treatment response. Risks
High consumption of red meat, smoking, obesity, and alcohol consumption are significant risk factors. Patient & Prescribing Data
Patients diagnosed with CRC at Komfo Anokye Teaching Hospital from 2017 to 2022.
Treatment availability is limited by resources, with targeted therapies being expensive and not covered by insurance.
Clinical Best Practices
Implement early detection strategies to improve survival rates. Enhance public awareness and education on CRC symptoms and screening. Strengthen healthcare infrastructure to facilitate timely diagnosis and treatment. References
