The antimicrobial potential of the secretome from Wharton’s jelly mesenchymal stem cells in the context of regenerative medicine: an in vitro study - Scorecard - MDSpire

The antimicrobial potential of the secretome from Wharton’s jelly mesenchymal stem cells in the context of regenerative medicine: an in vitro study

  • By

  • Filomena Napolitano

  • Emanuela Roscetto

  • Maria Fabozzi

  • Martina Aversa

  • Pietro Formisano

  • Maria Rosaria Catania

  • Nunzia Montuori

  • May 5, 2026

  • 0 min

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Clinical Scorecard: Exploring the Antimicrobial Properties of Wharton’s Jelly Mesenchymal Stem Cell Secretome in Regenerative Medicine: An In Vitro Investigation

At a Glance

CategoryDetail
Condition
Key Mechanisms
Target PopulationPatients with chronic wounds, including diabetic foot ulcers.
Care Setting

Key Highlights

  • WJ-MSC-CM exhibits notable antimicrobial effects against Staphylococcus aureus, which may reduce infection rates.
  • WJ-MSC-CM enhances antioxidant responses in dermal fibroblasts, potentially improving healing outcomes.

Guideline-Based Recommendations

Diagnosis

    Management

    • Consider WJ-MSC-CM as a cell-free therapeutic option for wound healing, particularly in patients with high infection risk.

    Monitoring & Follow-up

      Risks

        Patient & Prescribing Data

        WJ-MSC-CM may reduce the risk of infection and promote faster healing; assess for allergies to components.

        Clinical Best Practices

        • Utilize WJ-MSC-CM in conjunction with standard wound care protocols, supported by clinical evidence.
        • Monitor oxidative stress levels and patient response in those receiving WJ-MSC-CM.

        References

        Original Source(s)

        The antimicrobial potential of the secretome from Wharton’s jelly mesenchymal stem cells in the context of regenerative medicine: an in vitro study

        • by Filomena Napolitano, Emanuela Roscetto, Maria Fabozzi, Martina Aversa, Pietro Formisano, Maria Rosaria Catania, Nunzia Montuori

        • May 5, 2026

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