Effectiveness of manual therapy targeting hamstring tightness in knee osteoarthritis: a systematic review of rehabilitation outcomes - Scorecard - MDSpire

Effectiveness of manual therapy targeting hamstring tightness in knee osteoarthritis: a systematic review of rehabilitation outcomes

  • By

  • Saeid Yahia Al Matif

  • Hussain Al Dera

  • Thamer Al Shammary

  • Ahmed Al Mansour

  • Amirah Alotaibi

  • Mona Idris

  • July 2, 2026

  • 0 min

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Clinical Scorecard: Efficacy of Manual Therapy on Hamstring Tightness in Patients with Knee Osteoarthritis: A Systematic Review of Rehabilitation Results

At a Glance

CategoryDetail
ConditionKnee Osteoarthritis (KOA)
Key MechanismsManual therapy targeting hamstring tightness to modulate pain and improve function.
Target PopulationAdults with radiographically confirmed KOA.
Care SettingRehabilitation settings.

Key Highlights

  • Manual therapy showed significant pain reduction (1.5 to 3.2 points on VAS/NPRS).
  • Hamstring flexibility improved by 8 to 18 units.
  • Nine studies reported significant within-group improvements.
  • Moderate quality of evidence with PEDro scores ranging from 3 to 7.
  • Common biases included lack of therapist blinding and inadequate allocation concealment.

Guideline-Based Recommendations

Diagnosis

  • Use radiographs for classification of KOA severity.

Management

  • Consider manual therapy as an adjunct to exercise therapy for KOA.

Monitoring & Follow-up

  • Assess pain intensity and physical function using VAS/NPRS and WOMAC/KOOS.

Risks

  • Potential biases in study designs may affect the reliability of findings.

Patient & Prescribing Data

Adults with knee osteoarthritis experiencing hamstring tightness.

Manual therapy techniques such as post-isometric relaxation and soft-tissue mobilization may provide short-term benefits.

Clinical Best Practices

  • Incorporate manual therapy into rehabilitation protocols for KOA.
  • Utilize standardized protocols in future trials to enhance evidence quality.

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