Management of a Patient with Acute Appendicitis and Anaphylactic Shock Triggered by Esomeprazole: A Case Study
By
Jiangfeng Pu
Li Xin
Yikuan Chen
Xuemei Jiang
September 8, 2026
Clinical Scorecard: Management of a Patient with Acute Appendicitis and Anaphylactic Shock Triggered by Esomeprazole: A Case Study
At a Glance
Category Detail
Condition Acute Appendicitis with Anaphylactic Shock Key Mechanisms Anaphylactic shock induced by esomeprazole leading to cardiac arrest. Target Population Adults experiencing acute appendicitis and drug-induced anaphylaxis. Care Setting Emergency and Intensive Care Units
Key Highlights
Anaphylactic shock from esomeprazole can lead to rapid deterioration, including cardiac arrest. Prompt recognition and intervention are critical for survival in cases of drug-induced anaphylaxis. VA-ECMO support was utilized after standard resuscitation failed. Multidisciplinary collaboration and precise nursing interventions contributed to a favorable outcome. The patient recovered after 48 days of intensive therapy. Guideline-Based Recommendations
Diagnosis
Recognize allergic manifestations promptly after drug administration. Management
Activate rapid response team and initiate cardiopulmonary resuscitation immediately. Consider VA-ECMO for refractory cardiac arrest. Monitoring & Follow-up
Dynamically monitor inflammatory markers and vital signs. Risks
Severe adverse reactions to esomeprazole, including anaphylaxis and cardiac arrest. Patient & Prescribing Data
Adults with acute appendicitis and no prior drug allergies.
Esomeprazole should be administered with caution in patients with potential for allergic reactions.
Clinical Best Practices
Implement targeted temperature management during critical care. Provide psychological support to patients recovering from severe allergic reactions. Related Resources & Content
