Exploring the influencing factors of initial seizure time during modified electroconvulsive therapy in patients under 30 years old with mental disorders - Scorecard - MDSpire

Exploring the influencing factors of initial seizure time during modified electroconvulsive therapy in patients under 30 years old with mental disorders

  • By

  • Wanwen Li

  • Mingjian Cai

  • Xiaoli Sun

  • Huali Huang

  • Chao Ding

  • Shuang Fu

  • Changjiang Zhu

  • July 8, 2026

  • 0 min

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Clinical Scorecard: Identifying Factors Affecting Initial Seizure Duration in Patients Under 30 with Mental Disorders During Modified Electroconvulsive Therapy

At a Glance

CategoryDetail
ConditionModified Electroconvulsive Therapy (MECT)
Key MechanismsAge, energy percentage, and etomidate dose influence seizure duration.
Target PopulationPatients under 30 years old with mental disorders (depression, bipolar disorder, schizophrenia).
Care SettingMental health treatment facilities performing MECT.

Key Highlights

  • Study included 287 patients under 30 years old.
  • Ideal seizure duration is defined as 15-75 seconds.
  • Age, energy percentage, and etomidate dose are critical predictors of seizure duration.
  • Traditional energy settings often lead to prolonged seizure durations in younger patients.
  • Optimized initial energy percentage is recommended to be 1/3–2/5 of the patient's age.

Guideline-Based Recommendations

Diagnosis

  • Patients diagnosed with depression, bipolar disorder, or schizophrenia per ICD-11.

Management

  • Use etomidate anesthesia with adjusted doses and energy settings based on age.

Monitoring & Follow-up

  • Real-time EEG seizure duration, SpO2, heart rate, and blood pressure should be monitored.

Risks

  • Prolonged seizure durations increase risks of cognitive impairment and delirium.

Patient & Prescribing Data

Young adults and adolescents under 30 years with mental disorders.

Initial energy percentage should be set to 1/3–2/5 of the patient's age to optimize seizure duration.

Clinical Best Practices

  • Implement a standardized protocol for initial energy settings in MECT for patients under 30.
  • Utilize a classification model to predict seizure duration based on key factors.

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