Granulocyte colony-stimulating factor-induced hypersensitivity reaction with leukocytosis in a pediatric germ cell tumor patient: a case report - Scorecard - MDSpire

Granulocyte colony-stimulating factor-induced hypersensitivity reaction with leukocytosis in a pediatric germ cell tumor patient: a case report

  • By

  • Yuhui Tan

  • Chaoyong Wei

  • Wenyan Xiao

  • Yilan Fu

  • Xi Chen

  • Yanxiang Tang

  • Changli Tang

  • June 8, 2026

  • 0 min

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Clinical Scorecard: Hypersensitivity Reaction and Leukocytosis Induced by Granulocyte Colony-Stimulating Factor in a Pediatric Patient with Germ Cell Tumor: A Case Study

At a Glance

CategoryDetail
Condition
Key Mechanisms
Target PopulationPediatric patients (ages 0-18) with germ cell tumors undergoing chemotherapy.
Care Setting

Key Highlights

  • Patient previously tolerated G-CSF without adverse events.

Guideline-Based Recommendations

Diagnosis

    Management

    • Immediate administration of epinephrine (0.01 mg/kg) for anaphylactic reactions.

    Monitoring & Follow-up

      Risks

        Patient & Prescribing Data

        Prophylactic G-CSF administration is common in pediatric oncology but may lead to severe adverse reactions.

        Clinical Best Practices

        • Document any allergic reactions in patient records for future reference.

        Related Resources & Content

        Original Source(s)

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