Prevalence of Human Papillomavirus Genotypes Among Reproductive-Aged Women in Madagascar's Boeny Region: A Cross-Sectional Analysis of HPV Vaccination Needs and Opportunities - Scorecard - MDSpire

Prevalence of Human Papillomavirus Genotypes Among Reproductive-Aged Women in Madagascar's Boeny Region: A Cross-Sectional Analysis of HPV Vaccination Needs and Opportunities

  • By

  • Ekaterine Garsevanidze

  • Irina Kislaya

  • Jean-Marc Kutz

  • Tahinamandranto Rasamoelina

  • Sonya Ratefiarisoa

  • Ravo Razafindrakoto

  • Zaraniaina Tahiry Rasolojaona

  • Nantenaina Mathieu Razafindralava

  • Olivette Totofotsy

  • Alexina Olivasoa Zafinimampera

  • Tiana Randrianarisoa

  • Myriam Lassmann

  • Aaron Remkes

  • André Brito

  • Diavolana Koecher Andrianarimanana

  • Rivo Solotiana Rakotomalala

  • Zoly Rakotomalala

  • Pia Rausche

  • Jana Hey

  • Sandrine McKay-Chopin

  • Jürgen May

  • Monika Hampl

  • Valentina Marchese

  • Tarik Gheit

  • Rivo Andry Rakotoarivelo

  • Daniela Fusco

  • January 28, 2026

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Clinical Scorecard: Prevalence of Human Papillomavirus Genotypes Among Reproductive-Aged Women in Madagascar's Boeny Region: A Cross-Sectional Analysis of HPV Vaccination Needs and Opportunities

At a Glance

CategoryDetail
ConditionHuman Papillomavirus (HPV) infection
Key MechanismsInfection of basal keratinocytes leading to various diseases and cancers, particularly cervical cancer.
Target PopulationWomen aged 18-49 years in Madagascar's Boeny region.
Care SettingPrimary Health Care Centres (PHCCs)

Key Highlights

  • HPV is the most prevalent sexually transmitted infection globally.
  • Cervical cancer is the most common HPV-attributable cancer, primarily associated with high-risk HPV types.
  • Madagascar has a high HPV prevalence (>36%) and cervical cancer incidence (41.2 per 100,000 women).
  • HPV vaccination programs are critical for reducing cervical cancer incidence.
  • Implementation of HPV vaccination in Madagascar faces significant challenges.

Guideline-Based Recommendations

Diagnosis

  • Use cervico-vaginal lavage (CVL) samples for HPV genotyping.

Management

  • Implement HPV vaccination programs targeting girls by age 15.

Monitoring & Follow-up

  • Screen 70% of women using high-performance tests by ages 35 and 45.

Risks

  • High prevalence of HPV and cervical cancer due to lack of preventive measures.

Patient & Prescribing Data

Women of reproductive age in Madagascar's Boeny region.

Vaccination could reduce HPV-related precancerous lesions and cervical cancer by 70-90%.

Clinical Best Practices

  • Encourage HPV vaccination as part of routine immunization.
  • Educate women on the importance of cervical cancer screening.
  • Address logistical and socio-cultural barriers to vaccination.

References

Original Source(s)

Prevalence of Human Papillomavirus Genotypes Among Reproductive-Aged Women in Madagascar's Boeny Region: A Cross-Sectional Analysis of HPV Vaccination Needs and Opportunities

  • by Ekaterine Garsevanidze, Irina Kislaya, Jean-Marc Kutz, Tahinamandranto Rasamoelina, Sonya Ratefiarisoa, Ravo Razafindrakoto, Zaraniaina Tahiry Rasolojaona, Nantenaina Mathieu Razafindralava, Olivette Totofotsy, Alexina Olivasoa Zafinimampera, Tiana Randrianarisoa, Myriam Lassmann, Aaron Remkes, André Brito, Diavolana Koecher Andrianarimanana, Rivo Solotiana Rakotomalala, Zoly Rakotomalala, Pia Rausche, Jana Hey, Sandrine McKay-Chopin, Jürgen May, Monika Hampl, Valentina Marchese, Tarik Gheit, Rivo Andry Rakotoarivelo, Daniela Fusco

  • January 28, 2026

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