Perceived stress and depression among Chinese nurses: a cross-sectional mediation analysis of psychological flexibility and its components - Scorecard - MDSpire

Perceived stress and depression among Chinese nurses: a cross-sectional mediation analysis of psychological flexibility and its components

  • By

  • Zeyu Huang

  • Pan Diao

  • Tian Tian

  • Lei Yang

  • Xiaomei Li

  • May 28, 2026

  • 0 min

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Clinical Scorecard: Stress Perception and Depression in Chinese Nurses: A Cross-Sectional Analysis of Psychological Flexibility and Its Mediating Factors

At a Glance

CategoryDetail
ConditionDepression among nurses
Key MechanismsPerceived stress and psychological flexibility
Target PopulationNurses in China
Care SettingTertiary Grade A public hospitals

Key Highlights

  • Depression prevalence among nurses is 26%.
  • Perceived stress is positively correlated with depression (r = 0.63, p < 0.01).
  • Psychological flexibility partially mediates the relationship between perceived stress and depression.
  • Components of psychological flexibility include acceptance, cognitive defusion, mindfulness, and committed action.
  • Indirect associations through mindfulness and self-as-context were not significant.

Guideline-Based Recommendations

Diagnosis

  • Utilize the Patient Health Questionnaire-9 for assessing depression.

Management

  • Consider interventions targeting psychological flexibility to mitigate depression.

Monitoring & Follow-up

  • Regularly assess perceived stress levels among nursing staff.

Risks

  • High perceived stress is linked to increased depression and poorer quality of care.

Patient & Prescribing Data

Nurses experiencing high levels of stress.

Psychological flexibility may serve as a target for interventions.

Clinical Best Practices

  • Implement stress management programs focusing on enhancing psychological flexibility.
  • Monitor mental health outcomes in nursing staff regularly.

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