Taming “The Monster” – with Koen Sandra - Scorecard - MDSpire

Taming “The Monster” – with Koen Sandra

Ahead of ISC2026 in Prague, Koen Sandra explores how analytical scientists are rising to the challenge posed by increasingly intimidating biotherapeutics

  • June 9, 2026

  • 11 min

Share

Clinical Scorecard: Taming “The Monster” – with Koen Sandra

At a Glance

CategoryDetail
Condition
Key Mechanisms
Target PopulationAnalytical scientists and biopharmaceutical researchers focusing on complex therapeutics.
Care Setting

Key Highlights

  • Focus on complex biotherapeutics including antibody-oligonucleotide conjugates and their analytical challenges.

Guideline-Based Recommendations

Diagnosis

  • Consider molecular characterization techniques for accurate diagnosis.

Management

  • Implement integrated analytical workflows for managing complex biotherapeutics.

Monitoring & Follow-up

  • Regularly assess the stability and efficacy of biopharmaceuticals using advanced analytics.

Risks

  • Identify potential analytical pitfalls in characterizing novel biotherapeutics.

Patient & Prescribing Data

Patients receiving biopharmaceutical therapies requiring complex analytical characterization.

Clinical Best Practices

  • Utilize orthogonal, high-resolution analytics for complex molecules, such as LC-MS and NMR.
  • Consolidate multiple assays into single platforms for efficiency, improving throughput and reducing costs.
  • Engage in continuous knowledge sharing and collaboration among scientists to foster innovation.

Related Resources & Content

    Original Source(s)

    Taming “The Monster” – with Koen Sandra

    • June 9, 2026

    Related Content

    Paper Diagnostics Meet Cancer Biomarkers

    A microfluidic paper platform detects microRNA in spiked serum samples using a simple color-based readout

    • June 10, 2026

    • 2 min
    Holding the Line: Sitting Down With Mario Thevis

    At the forefront of anti-doping science, Mario Thevis reflects on evolving detection strategies, new classes of performance-enhancing drugs, and the growing complexity of keeping sport clean

    My Mentoring Inspiration: My Mother

    Gang He shares memories of the woman who taught him how to help others succeed