Current status and research hotspots of pediatric nephrotic syndrome: a bibliometric analysis (2011–2025) - Scorecard - MDSpire

Current status and research hotspots of pediatric nephrotic syndrome: a bibliometric analysis (2011–2025)

  • By

  • Wenyin Yang

  • Yu Pei

  • Chaoyang Wang

  • Mingxia Tang

  • Jiadong Xie

  • Jing Zhao

  • July 9, 2026

  • 0 min

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Clinical Scorecard: Pediatric Nephrotic Syndrome: A Bibliometric Review of Current Trends and Research Focuses (2011–2025)

At a Glance

CategoryDetail
ConditionPediatric Nephrotic Syndrome
Key MechanismsImmune dysregulation, circulating factors, podocyte dysfunction
Target PopulationChildren with nephrotic syndrome
Care SettingPediatric nephrology research

Key Highlights

  • Total of 2,873 publications analyzed from 2011 to 2025
  • China contributed the most articles (452 publications)
  • Key topics include nephrotic syndrome, children, and focal segmental glomerulosclerosis
  • Emerging keywords include leukocyte count and lipoid nephrosis
  • Assistance Publique Hopitaux Paris had the highest number of publications (77)

Guideline-Based Recommendations

Diagnosis

  • Characterized by massive proteinuria (>3.5 g/24 h), hypoalbuminemia, hyperlipidemia, and edema

Management

  • Advancements in immunosuppressive regimens and biological agents such as Rituximab

Monitoring & Follow-up

    Risks

    • Frequent relapses and long-term complications of treatment

    Patient & Prescribing Data

    Children diagnosed with nephrotic syndrome

    Focus on novel immunosuppressants and understanding pathogenic mechanisms

    Clinical Best Practices

    • Utilize bibliometric analysis for evaluating research trends
    • Collaborate globally to optimize management strategies

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