Age-related changes in lens thickness in children aged 3-17 years and its association with myopia and ocular biological parameters: a cross-sectional and longitudinal study - Scorecard - MDSpire
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Age-related changes in lens thickness in children aged 3-17 years and its association with myopia and ocular biological parameters: a cross-sectional and longitudinal study
Clinical Scorecard: Investigating the Impact of Age on Lens Thickness in Children Aged 3 to 17 Years and Its Relationship with Myopia and Ocular Measurements: A Cross-Sectional and Longitudinal Analysis
At a Glance
Category
Detail
Condition
Lens Thickness Changes in Children
Key Mechanisms
Age-related changes in lens thickness associated with ocular biometrics and refractive status.
Target Population
Children aged 3 to 17 years.
Care Setting
Ophthalmic examinations.
Key Highlights
Median lens thickness (LT) was 3.42 mm, negatively correlated with age.
Significant decrease in LT before age 10, stabilization at ages 10-12, and mild thickening after age 13.
Females had thicker LT than males.
Non-myopic children exhibited thicker LT compared to myopic children.
Age 10 is identified as a critical intervention window for refractive status assessment.
Guideline-Based Recommendations
Diagnosis
Monitor lens thickness as a potential biomarker for pediatric refractive status.
Management
Consider age-related changes in lens thickness when assessing refractive development.
Monitoring & Follow-up
Follow longitudinal changes in lens thickness from ages 3 to 17.
Risks
Increased risk of myopia associated with thinner lens thickness.
Patient & Prescribing Data
Children aged 3 to 17 years undergoing ophthalmic evaluations.
Thicker lenses in non-myopic children suggest potential compensatory mechanisms in refractive development.
Clinical Best Practices
Utilize lens thickness measurements in conjunction with other ocular biometrics for comprehensive assessments.
Identify critical ages for intervention to prevent or manage myopia.
