Transthoracic echocardiography in children with Staphylococcus aureus bacteraemia: a multi-centre retrospective analysis - Scorecard - MDSpire

Transthoracic echocardiography in children with Staphylococcus aureus bacteraemia: a multi-centre retrospective analysis

  • By

  • Kirsty Gray

  • Farhana Ahad

  • Aubrey Cunnington

  • June 19, 2026

  • 0 min

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Clinical Scorecard: Transthoracic Echocardiography Utilization in Pediatric Patients with Staphylococcus aureus Bacteraemia: A Retrospective Study Across Multiple Centers

At a Glance

CategoryDetail
ConditionStaphylococcus aureus bacteraemia (SAB)
Key MechanismsRisk of infective endocarditis (IE) associated with SAB, particularly in children with established risk factors.
Target PopulationChildren aged ≤18 years with SAB.
Care SettingMulti-centre pediatric care across North West London hospitals.

Key Highlights

  • 5.6% of children undergoing TTE were diagnosed with infective endocarditis.
  • All IE cases were in children with established risk factors.
  • TTE group had longer hospital stays compared to the no-TTE group (median 17 vs 4 days).
  • Embolic phenomena and persistent bacteraemia were significantly associated with IE.

Guideline-Based Recommendations

Diagnosis

  • Consider TTE in children with SAB who have established risk factors for IE.

Management

  • Perform TTE when clinical features suggestive of IE are present.

Monitoring & Follow-up

  • Monitor for embolic phenomena, persistent bacteraemia, and other clinical signs indicative of IE.

Risks

  • Increased length of hospital stay and potential for unnecessary investigations in low-risk children.

Patient & Prescribing Data

Children diagnosed with SAB across six hospitals.

Risk-stratified approach to TTE may reduce unnecessary procedures in low-risk patients.

Clinical Best Practices

  • Utilize a risk-stratified approach for TTE in pediatric SAB cases.
  • Avoid TTE in children with structurally normal hearts and no established risk factors.

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