Innovative One-Handed Syringe Handle Design for Anterior Chamber Paracentesis
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By
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Liangbo Linus Shen
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Jay M. Stewart
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Mitchel A. Cole
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Madelynn E. Mackenzie
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Frank Brodie
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November 28, 2025
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Clinical Scorecard: Innovative One-Handed Syringe Handle Design for Anterior Chamber Paracentesis
At a Glance
| Category | Detail |
|---|
| Condition | Anterior Chamber Paracentesis |
| Key Mechanisms | Collection of aqueous humor for diagnostic and therapeutic purposes. |
| Target Population | Ophthalmology residents and patients requiring AC paracentesis. |
| Care Setting | In-office ophthalmic procedure. |
Key Highlights
- Novel one-handed syringe handle improves safety and control during AC paracentesis.
- All procedures with the novel device achieved ≥ 100 µL fluid aspiration without intraocular injuries.
- Participants reported increased confidence and satisfaction with the novel device.
Guideline-Based Recommendations
Diagnosis
- Use AC paracentesis for diagnosing uveitis, endophthalmitis, or lymphoma.
Management
- Rapidly lower intraocular pressure in glaucoma or during intravitreal injections.
Monitoring & Follow-up
- Observe for complications such as trauma to ocular structures and intraocular pressure changes.
Risks
- Potential complications include corneal, iris, or lens trauma, hyphema, keratitis, and endophthalmitis.
Patient & Prescribing Data
Patients undergoing procedures requiring aqueous humor analysis or intraocular pressure management.
The novel device allows for safer and more controlled fluid aspiration.
Clinical Best Practices
- Utilize the novel one-handed syringe handle to enhance procedural safety and efficiency.
- Ensure proper stabilization of the globe during the procedure to minimize risk.
References
