Clinical and Imaging Characteristics of Severe Mpox: A Case Study Involving 16 Patients from Beijing, China
By
Fuchun Wang
Yuan Fang
Zhongkai Zhou
Hao Liu
Jiahao Ji
Lin Jia
Han Jia
Luyao Zheng
Wen Wang
Caiping Guo
Chunwang Yuan
Yue Yin
Juming Ma
Hongjun Li
Budong Chen
Junyi Duan
Tao Huang
Guanghui Zhang
Taiyi Jiang
Tong Zhang
Wei Wang
January 20, 2026
Clinical Scorecard: Clinical and Imaging Characteristics of Severe Mpox: A Case Study Involving 16 Patients from Beijing, China
At a Glance
Category Detail
Condition Severe Mpox (Monkeypox) Key Mechanisms Zoonotic viral infection caused by MPXV, primarily transmitted through direct contact with lesions or bodily fluids. Target Population Individuals diagnosed with severe mpox, particularly those co-infected with HIV. Care Setting Single-center retrospective case series at Beijing Youan Hospital.
Key Highlights
Severe mpox cases often present with disseminated infections affecting multiple organs. High prevalence of severe cases among men who have sex with men (MSM) and individuals co-infected with HIV. Imaging plays a crucial role in diagnosing and monitoring severe mpox complications. Guideline-Based Recommendations
Diagnosis
Confirmed by positive PCR test for MPXV with Ct value < 40. Management
Severe cases may require surgical intervention for necrotic lesions. Monitoring & Follow-up
Regular imaging assessments to evaluate complications and disease progression. Risks
Increased mortality rate associated with severe mpox, especially in immunocompromised individuals. Patient & Prescribing Data
16 patients with severe mpox co-infected with HIV.
Management strategies should consider the presence of HIV and associated complications.
Clinical Best Practices
Early diagnosis through PCR testing is critical for effective management. Monitor for complications such as secondary infections and organ involvement. Consider the patient's immune status when assessing severity and treatment options. Related Resources & Content
