Comparative Study on the Efficacy and Safety of Different Left Atrial Appendage Occluders in One-Stop Atrial Fibrillation Procedures - Scorecard - MDSpire

Comparative Study on the Efficacy and Safety of Different Left Atrial Appendage Occluders in One-Stop Atrial Fibrillation Procedures

  • By

  • Ren, Haoqiang

  • Lai, Hengli

  • May 8, 2026

  • 0 min

Share

Clinical Scorecard: Evaluation of Efficacy and Safety Among Various Left Atrial Appendage Occluders in Combined Atrial Fibrillation Treatment Procedures

At a Glance

CategoryDetail
ConditionAtrial Fibrillation (AF)
Key MechanismsComparison of sealing efficacy and safety of LAA occluders during catheter ablation and LAA occlusion.
Target PopulationPatients with atrial fibrillation undergoing one-stop procedures.
Care SettingRetrospective analysis in a clinical setting.

Key Highlights

  • Study analyzed 231 AF patients with three types of LAA occluders.
  • No significant differences in peri-device leak rates among WATCHMAN, LAmbre, and LACBES.
  • CHA₂DS₂-VASc score identified as an independent risk factor for peri-device leak.
  • Older age was found to be a protective factor against peri-device leak.
  • No significant differences in device-related thrombus or stroke incidence.

Guideline-Based Recommendations

Diagnosis

    Management

      Monitoring & Follow-up

      • Closer monitoring recommended for patients with high CHA₂DS₂-VASc scores and younger age.

      Risks

      • Higher CHA₂DS₂-VASc score is a risk factor for peri-device leak.

      Patient & Prescribing Data

      231 patients with atrial fibrillation undergoing LAA occlusion.

      WATCHMAN, LAmbre, and LACBES occluders show comparable effectiveness.

      Clinical Best Practices

      • Consider CHA₂DS₂-VASc score in risk assessment for peri-device leak.
      • Evaluate patient age as a factor in monitoring strategies.

      Related Resources & Content

        Original Source(s)

        Related Content