Three-Dimensional Transthoracic Echocardiography as a Tool for Patient Selection for Percutaneous Atrial Septal Defect Closure - Scorecard - MDSpire
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Utilizing Three-Dimensional Transthoracic Echocardiography for Selecting Candidates for Percutaneous Closure of Atrial Septal Defects

  • By

  • Talya Finke

  • Uriel Katz

  • Tal Grupel

  • Yarden Sarouf Gat

  • Gur Mainzer

  • Sharon Borik Chiger

  • September 12, 2026

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Clinical Scorecard: Utilizing Three-Dimensional Transthoracic Echocardiography for Selecting Candidates for Percutaneous Closure of Atrial Septal Defects

At a Glance

Category

Detail

Condition

Atrial Septal Defects

Key Mechanisms

Three-dimensional transthoracic echocardiography provides reliable measurements for defect evaluation and selection for closure procedures.

Target Population

Patients aged 1-44 years referred for atrial septal defect closure.

Care Setting

Pediatric cardiology clinic

Key Highlights

  • Three-dimensional transthoracic echocardiography is increasingly used for patient selection in percutaneous closure.

  • It offers a low-risk alternative to sedation-required imaging techniques.

  • The study evaluated 36 cases over three years, with a median patient age of 6 years.

  • Direct surgical referral occurred in 42% of cases due to anatomical concerns.

  • Patients referred for three-dimensional echocardiography often had inconclusive initial imaging.

Guideline-Based Recommendations

Diagnosis

  • Use three-dimensional transthoracic echocardiography for accurate assessment of atrial septal defects.

Management

  • Refer appropriate candidates for percutaneous closure based on three-dimensional imaging results.

Monitoring & Follow-up

  • Monitor patients for complications post-intervention, particularly in those undergoing surgical repair.

Risks

  • Consider risks associated with large defects and inadequate rims when evaluating for percutaneous closure.

Patient & Prescribing Data

Children and young adults aged 1-44 years with atrial septal defects.

Patients with large defects or inadequate rims are more likely to be referred for surgical closure.

Clinical Best Practices

  • Utilize a multidisciplinary team approach for evaluating candidates for closure.

  • Ensure all three-dimensional echocardiograms are performed by a dedicated pediatric cardiology specialist.

  • Discuss cases in a cardiac conference to determine the best closure strategy.

Related Resources & Content

  1. 2025 ACC/AHA/HRS/ISACHD/SCAI Guideline for the Management of Adults With Congenital Heart Disease: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines | Circulation

  2. SCAI Position Statement on Intracardiac Echocardiography to Guide Structural Heart Disease Interventions - PMC

  3. Routine application of three-dimensional transesophageal echocardiography-based device selection for transcatheter closure of atrial septal defect without balloon sizing | European Heart Journal - Cardiovascular Imaging | Oxford Academic

  4. Pediatric Cardiology — A New Modification of Temporary Suture-Holding Technique for Transcatheter Repair of Sinus Venosus Atrial Septal Defect

  5. Surgical Endoscopy — Endoscopic Closure of Atrial Septal Defects in Functioning Beating Hearts

  6. Int. Journal of Computer Assisted Radiology and Surgery — Development and feasibility testing of a dynamic image-derived simulation framework for assessing left atrioventricular valve repair strategies

  7. Frontiers in Cardiovascular Medicine — Assessment of the Viability and Initial Results of Transcatheter Closure for Moderate-to-Large Perimembranous Ventricular Septal Defects in Pediatric Patients Using Bioabsorbable Occluders: A Prospective Case Study

  8. 2025 ACC/AHA/HRS/ISACHD/SCAI Guideline for the Management of Adults With Congenital Heart Disease: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines | Circulation

  9. SCAI Position Statement on Intracardiac Echocardiography to Guide Structural Heart Disease Interventions - PMC

  10. Routine application of three-dimensional transesophageal echocardiography-based device selection for transcatheter closure of atrial septal defect without balloon sizing | European Heart Journal - Cardiovascular Imaging | Oxford Academic

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