Utilizing Three-Dimensional Transthoracic Echocardiography for Selecting Candidates for Percutaneous Closure of Atrial Septal Defects
By
Talya Finke
Uriel Katz
Tal Grupel
Yarden Sarouf Gat
Gur Mainzer
Sharon Borik Chiger
September 12, 2026
Clinical Scorecard: Utilizing Three-Dimensional Transthoracic Echocardiography for Selecting Candidates for Percutaneous Closure of Atrial Septal Defects
At a Glance
Category Detail
Condition Atrial Septal Defects
Key Mechanisms Three-dimensional transthoracic echocardiography provides reliable measurements for defect evaluation and selection for closure procedures.
Target Population Patients aged 1-44 years referred for atrial septal defect closure.
Care Setting Pediatric cardiology clinic
Key Highlights
Three-dimensional transthoracic echocardiography is increasingly used for patient selection in percutaneous closure. It offers a low-risk alternative to sedation-required imaging techniques. The study evaluated 36 cases over three years, with a median patient age of 6 years. Direct surgical referral occurred in 42% of cases due to anatomical concerns. Patients referred for three-dimensional echocardiography often had inconclusive initial imaging.
Guideline-Based Recommendations
Diagnosis
Use three-dimensional transthoracic echocardiography for accurate assessment of atrial septal defects.
Management
Refer appropriate candidates for percutaneous closure based on three-dimensional imaging results.
Monitoring & Follow-up
Monitor patients for complications post-intervention, particularly in those undergoing surgical repair.
Risks
Consider risks associated with large defects and inadequate rims when evaluating for percutaneous closure.
Patient & Prescribing Data
Children and young adults aged 1-44 years with atrial septal defects.
Patients with large defects or inadequate rims are more likely to be referred for surgical closure.
Clinical Best Practices
Utilize a multidisciplinary team approach for evaluating candidates for closure. Ensure all three-dimensional echocardiograms are performed by a dedicated pediatric cardiology specialist. Discuss cases in a cardiac conference to determine the best closure strategy.
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