The Take 5 Campaign: Effects of an Intervention to Promote Five-Day Durations of Antibiotic Therapy for Common Infections in Urgent Care - Scorecard - MDSpire

The Take 5 Campaign: Effects of an Intervention to Promote Five-Day Durations of Antibiotic Therapy for Common Infections in Urgent Care

  • By

  • Timothy C Jenkins

  • Axel A Vazquez Deida

  • Lindsey E Fish

  • Michael J Breyer

  • Amy Quinones

  • Melody Zwakenberg

  • Cory K Hussain

  • Allison L Sabel

  • Katherine C Shihadeh

  • September 8, 2025

  • 0 min

Share

Clinical Scorecard: The Take 5 Initiative: Impact of a Program to Encourage Five-Day Antibiotic Treatment for Common Infections in Urgent Care Settings

At a Glance

CategoryDetail
ConditionCommon infections including skin and soft tissue infections, urinary tract infections, sinusitis, otitis media, pneumonia, and COPD exacerbations
Key MechanismsPromotion of 5-day antibiotic therapy durations aligned with institutional guidelines to reduce unnecessary antibiotic exposure
Target PopulationPatients aged 18 years and older presenting to urgent care centers with target infections
Care SettingUrgent care centers within an integrated health care system

Key Highlights

  • The Take 5 campaign increased the proportion of antibiotic prescriptions for ≤5 days from 57.5% to 82.9%.
  • No significant differences were observed in rates of new antibiotic prescriptions or hospitalizations within 14 days post-intervention.
  • Shortening antibiotic durations in urgent care is an effective strategy to reduce unnecessary antibiotic exposure without compromising clinical outcomes.

Guideline-Based Recommendations

Diagnosis

  • Identify infections where antibiotics are indicated: cellulitis or drained skin abscesses, acute cystitis, acute bacterial sinusitis, community-acquired pneumonia, acute COPD exacerbations, acute otitis media, and acute pyelonephritis (with fluoroquinolone use).

Management

  • Prescribe antibiotic durations of 5 days or fewer for the specified infections according to institutional guidance.
  • Utilize institutional antibiotic stewardship resources such as the antibiotic stewardship app for treatment recommendations.

Monitoring & Follow-up

  • Monitor for new antibiotic prescriptions and hospitalizations within 14 days to assess clinical outcomes post-treatment.

Risks

  • Avoid unnecessarily prolonged antibiotic courses to reduce antibiotic exposure and potential resistance.
  • Ensure adherence to recommended durations to maintain clinical effectiveness and minimize adverse events.

Patient & Prescribing Data

Adults (≥18 years) treated for common infections in urgent care settings

Implementation of the Take 5 campaign led to a significant and sustained increase in adherence to 5-day antibiotic durations without increasing adverse clinical outcomes.

Clinical Best Practices

  • Engage clinical leadership and peer champions to promote adherence to antibiotic duration guidelines.
  • Provide education sessions and distribute informational materials to clinicians to support guideline adoption.
  • Leverage institutional stewardship tools such as smartphone apps to facilitate access to treatment recommendations.
  • Use interrupted time-series analysis to monitor prescribing trends and intervention impact.

References

Original Source(s)

Related Content