Global research trends and emerging frontiers of intratumoral microbiota in cancer immunotherapy: a bibliometric and visualization analysis - Scorecard - MDSpire

Worldwide Research Patterns and New Developments in Intratumoral Microbiota's Role in Cancer Immunotherapy: A Bibliometric and Visualization Study

  • By

  • Jiahe Zhou

  • Heyun Tao

  • Fuzhu Zou

  • Huiying Guo

  • Ruo Ding

  • Qing Lei

  • Xiaodie Zhou

  • Si Mei

  • July 21, 2026

Share

Clinical Scorecard: Worldwide Research Patterns and New Developments in Intratumoral Microbiota's Role in Cancer Immunotherapy: A Bibliometric and Visualization Study

At a Glance

CategoryDetail
ConditionIntratumoral microbiota in cancer immunotherapy
Key MechanismsInfluences tumor immune microenvironment (TIME) and responses to immune checkpoint inhibitors (ICIs)
Target PopulationPatients undergoing cancer immunotherapy
Care SettingResearch and clinical development in oncology

Key Highlights

  • 245 publications analyzed, with a CAGR of 63.1% from 2017 to 2024
  • China and the United States are leading in publication output and citations
  • Research hotspots are shifting towards immunotherapy resistance and microbiota-targeted interventions
  • Keyword analysis indicates 'intratumoral microbiota' as the most frequent term
  • Frontiers in Immunology is the most productive journal in this field

Guideline-Based Recommendations

Diagnosis

    Management

      Monitoring & Follow-up

        Risks

          Patient & Prescribing Data

          Cancer patients receiving immunotherapy

          Potential role of intratumoral microbiota in predicting treatment response

          Clinical Best Practices

          • Prioritize standardized detection of intratumoral microbiota
          • Focus on spatial and multi-omics validation
          • Encourage multicenter prospective evaluations for clinical translation

          Related Resources & Content

          Original Source(s)

          Related Content