Greater amounts of visceral adipose and lean body mass increase heart failure risk in older women - Scorecard - MDSpire

Greater amounts of visceral adipose and lean body mass increase heart failure risk in older women

  • By

  • Michael J. LaMonte

  • Charles B. Eaton

  • Bernhard Haring

  • Jennifer W. Bea

  • Connor R. Miller

  • JoAnn E. Manson

  • Deepika Laddu

  • Marcia L. Stefanick

  • Andrew Odegaard

  • May 26, 2026

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Clinical Scorecard: Higher levels of visceral fat and lean mass elevate heart failure risk among older women

At a Glance

CategoryDetail
Condition
Key MechanismsVisceral adipose tissue (VAT) is hypothesized to have adverse effects, while lean mass is considered protective. [Needs attribution]
Target Population
Care Setting

Key Highlights

  • HF prevalence is increasing among adults aged ≥ 65 years, particularly in women.
  • Visceral fat and lean mass are associated with heart failure risk.
  • The study utilized dual energy x-ray absorptiometry (DXA) for body composition measurement.
  • Heart failure subtypes (HFpEF and HFrEF) were defined based on ejection fraction.
  • The study cohort included 161,808 postmenopausal women.

Guideline-Based Recommendations

Diagnosis

    Management

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    Monitoring & Follow-up

      Risks

        Patient & Prescribing Data

        Focus on managing body composition to mitigate heart failure risk. [Needs attribution]

        Clinical Best Practices

        • consider

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        Original Source(s)

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