The Holy Grail of Cataract Surgery
Accommodative intraocular lenses under investigation show promise for restoring a full range of vision in the pseudophakic patient.
By
Despoina Theotoka, MD, MSc
Kendall E. Donaldson, MD, MS
September 1, 2025
Clinical Scorecard: The Holy Grail of Cataract Surgery
At a Glance
Category Detail
Condition Presbyopia in pseudophakic patients Key Mechanisms Restoration of accommodation through innovative intraocular lenses (IOLs) Target Population Aging patients undergoing cataract surgery Care Setting Ophthalmology clinics and surgical centers
Key Highlights
Accommodating IOLs aim to restore natural vision lost to presbyopia. Multiple innovative accommodating IOLs are in development or early use. Clinical outcomes are promising but not yet definitive. Guideline-Based Recommendations
Diagnosis
Assess presbyopia in patients undergoing cataract surgery. Management
Consider accommodating IOLs for restoration of vision in pseudophakic patients. Monitoring & Follow-up
Evaluate visual acuity and accommodation post-implantation. Risks
Monitor for mixed clinical outcomes and potential complications. Patient & Prescribing Data
Pseudophakic patients with presbyopia
Accommodating IOLs like FluidVision, Juvene, OmniVu, and JelliSee show varying degrees of success in restoring vision.
Clinical Best Practices
Utilize FDA-approved accommodating lenses where applicable. Engage in ongoing clinical trials for emerging IOL technologies. Monitor patient outcomes closely to assess lens performance. Related Resources & Content
