Stair use and risk of incident rheumatic and non-rheumatic valvular heart disease: a cohort study from the UK biobank - Scorecard - MDSpire

Stair use and risk of incident rheumatic and non-rheumatic valvular heart disease: a cohort study from the UK biobank

  • By

  • Yabing Hou

  • Huichao Wu

  • Hongxi Yang

  • Zuolin Lu

  • June 29, 2026

  • 0 min

Share

Clinical Scorecard: Association Between Stair Climbing and the Development of Rheumatic and Non-Rheumatic Valvular Heart Disease: Findings from a UK Biobank Cohort Study

At a Glance

CategoryDetail
ConditionValvular Heart Disease (VHD)
Key MechanismsStair climbing is associated with reduced risk of incident VHD and its subtypes.
Target PopulationAdults aged 40-69 years from the UK Biobank study.
Care SettingPopulation-based cohort study

Key Highlights

  • 3.6% of participants developed new-onset VHD during a median follow-up of 13 years.
  • Climbing ≥160 steps per day was associated with a 20% reduced risk of VHD.
  • Significant reductions in risk were observed for both rheumatic and non-rheumatic valve diseases.

Guideline-Based Recommendations

Diagnosis

  • New-onset VHD defined using ICD-10 codes.

Management

  • Promote regular stair climbing as a preventive intervention for VHD.

Monitoring & Follow-up

  • Follow-up on stair climbing habits and incidence of VHD.

Risks

  • Participants with lower levels of total physical activity showed more pronounced benefits from stair climbing.

Patient & Prescribing Data

Participants from the UK Biobank aged 40-69 years.

Increased stair climbing is associated with lower incidence of VHD.

Clinical Best Practices

  • Encourage stair climbing as a simple, cost-effective form of physical activity.
  • Assess stair climbing frequency in routine evaluations of cardiovascular health.

Related Resources & Content

Original Source(s)

Related Content