Association of the inflammatory burden index with 1-year major adverse cardiovascular events in patients with HFpEF after myocardial infarction: a single-center retrospective cohort study - Scorecard - MDSpire
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Association of the inflammatory burden index with 1-year major adverse cardiovascular events in patients with HFpEF after myocardial infarction: a single-center retrospective cohort study
Clinical Scorecard: Link Between Inflammatory Burden Index and One-Year Major Adverse Cardiovascular Events in HFpEF Patients Following Myocardial Infarction: A Retrospective Cohort Analysis from a Single Center
At a Glance
Category
Detail
Condition
Heart Failure with Preserved Ejection Fraction (HFpEF) following Myocardial Infarction (MI)
Key Mechanisms
Inflammatory activation contributing to adverse remodeling and cardiovascular events
Target Population
Patients with HFpEF and documented MI
Care Setting
Single-center, retrospective cohort study
Key Highlights
Higher logIBI associated with 1-year major adverse cardiovascular events (MACE)
74 patients (12.5%) experienced MACE during follow-up
LogIBI improved risk discrimination in predicting MACE
C-index increased from 0.776 to 0.817 with logIBI addition
Decision curve analysis indicated higher net benefit with logIBI
Guideline-Based Recommendations
Diagnosis
HFpEF defined as symptomatic heart failure with LVEF ≥ 50%
MI identified according to contemporary clinical records
Management
Consider inflammatory markers like IBI in risk assessment post-MI
Monitoring & Follow-up
Follow-up for 1 year through outpatient records and electronic medical records
Risks
Patients with higher logIBI face increased risk of MACE
Patient & Prescribing Data
592 patients with HFpEF and documented MI
Inflammatory markers may guide management strategies
Clinical Best Practices
Integrate IBI in clinical assessments for HFpEF post-MI
Monitor inflammatory markers for risk stratification
