Admission hyperglycemia, in-hospital glycemic management, and discharge outcomes in acute ischemic stroke: a UAE comprehensive stroke center cohort - Scorecard - MDSpire
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Impact of Initial Hyperglycemia, In-Hospital Glycemic Control, and Discharge Results in Acute Ischemic Stroke: Findings from a Comprehensive Stroke Center in the UAE

  • By

  • Mohammed Hamad Al Kuwaiti

  • Virgie Guy Pedo

  • Adnan Agha

  • July 15, 2026

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Clinical Scorecard: Impact of Initial Hyperglycemia, In-Hospital Glycemic Control, and Discharge Results in Acute Ischemic Stroke: Findings from a Comprehensive Stroke Center in the UAE

At a Glance

CategoryDetail
ConditionAcute Ischemic Stroke
Key MechanismsImpaired collateral flow, blood–brain barrier disruption, oxidative injury, conversion of salvageable penumbra to infarction.
Target PopulationAdults with acute ischemic stroke.
Care SettingComprehensive stroke center.

Key Highlights

  • Admission hyperglycemia (51.7%) associated with unfavorable discharge outcomes.
  • Inappropriate management in 85.8% of hyperglycemic patients.
  • Routine HbA1c testing identified occult diabetes in 18.4% of patients.
  • No severe hypoglycemia occurred during the study.

Guideline-Based Recommendations

Diagnosis

  • Admission capillary glucose level >7.8 mmol/L indicates hyperglycemia.

Management

  • Treat hyperglycemia to a target of 7.8–10.0 mmol/L using subcutaneous insulin.

Monitoring & Follow-up

  • Structured admission orders and q6h monitoring recommended.

Risks

  • Intensive insulin protocols do not improve functional outcomes and increase severe hypoglycemia risk.

Patient & Prescribing Data

218 consecutive adults with acute ischemic stroke.

Adherence to SHINE trial-aligned management standards was low.

Clinical Best Practices

  • Implement structured admission orders for glycemic management.
  • Conduct routine HbA1c testing for undiagnosed diabetes.

Related Resources & Content

Original Source(s)

Admission hyperglycemia, in-hospital glycemic management, and discharge outcomes in acute ischemic stroke: a UAE comprehensive stroke center cohort

  • by Mohammed Hamad Al Kuwaiti, Virgie Guy Pedo, Adnan Agha

  • July 15, 2026

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