Prevalence and symptoms of incidental meningiomas: a population-based study - Scorecard - MDSpire

Prevalence and symptoms of incidental meningiomas: a population-based study

  • By

  • Eddie de Dios

  • Olivia Näslund

  • Mansor Choudhry

  • Marcus Berglund

  • Thomas Skoglund

  • Darko Sarovic

  • Lina Rydén

  • Silke Kern

  • Ingmar Skoog

  • Erik Thurin

  • April 3, 2025

  • 0 min

Share

Clinical Scorecard: Incidental Meningiomas: A Population-Based Analysis of Their Prevalence and Associated Symptoms

At a Glance

CategoryDetail
ConditionIncidental meningiomas, slow-growing extra-axial intracranial tumors from arachnoid cap cells
Key MechanismsExtra-axial tumor growth often asymptomatic; prevalence increases with age and is higher in women
Target PopulationOlder adults, specifically individuals aged 70 years and older
Care SettingPopulation-based screening and clinical imaging settings (MRI and CT)

Key Highlights

  • Meningiomas constitute about one third of all primary intracranial tumors and are more common in women.
  • Prevalence of asymptomatic meningiomas increases with age, with rates around 1–3% in older adults based on MRI and autopsy studies.
  • Incidental meningiomas are frequently discovered during imaging for non-specific symptoms, but causal relationship with symptoms like headache and dizziness is uncertain.

Guideline-Based Recommendations

Diagnosis

  • Use MRI and CT imaging to detect meningiomas, with careful radiological assessment including second readings for small incidental tumors.
  • Population-based imaging can reduce sampling bias compared to hospital-based cohorts.

Management

  • Adopt a wait-and-scan approach for asymptomatic meningiomas to minimize unnecessary surgery.
  • Avoid attributing vague symptoms such as headache and fatigue solely to incidental meningiomas without clear evidence.

Monitoring & Follow-up

  • Regular imaging follow-up may be warranted to monitor tumor growth in incidental meningiomas.
  • Clinical evaluation should include assessment of neurological symptoms and cognitive function.

Risks

  • Risk of unnecessary surgical intervention if symptoms are incorrectly attributed to incidental meningiomas.
  • Potential underestimation of meningioma prevalence due to variable imaging rates.

Patient & Prescribing Data

Individuals aged 70 years undergoing brain imaging in a population-based cohort

Most incidental meningiomas are asymptomatic; conservative management preferred unless symptoms or tumor growth indicate intervention.

Clinical Best Practices

  • Use population-based cohorts to assess true prevalence and symptom associations of incidental meningiomas.
  • Perform thorough clinical and radiological evaluation before attributing symptoms to meningiomas.
  • Ensure informed consent and ethical approval in studies involving brain imaging and clinical data collection.
  • Include multidisciplinary teams (radiologists, neurologists, psychiatrists) for comprehensive assessment.

References

Original Source(s)

Related Content