Effectiveness of a Behavior Change Wheel–Informed WeChat-Based Messaging Intervention to Improve Medication Adherence After Percutaneous Coronary Intervention: 12-Week Quasi-Experimental Study - Scorecard - MDSpire
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A Behavior Change Wheel–Guided WeChat Messaging Program to Enhance Medication Adherence After Percutaneous Coronary Intervention: A 12-Week Quasi-Experimental Study

  • By

  • Yong Fang

  • Wenxiao Wu

  • Dili Chen

  • Zhili Jiang

  • Mingyue Zhang

  • Fanghong Dong

  • Xinyue Xiang

  • Lihua Huang

  • October 7, 2026

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Clinical Scorecard: A Behavior Change Wheel–Guided WeChat Messaging Program to Enhance Medication Adherence After Percutaneous Coronary Intervention: A 12-Week Quasi-Experimental Study

At a Glance

CategoryDetail
ConditionMedication adherence after percutaneous coronary intervention (PCI) for coronary heart disease
Key MechanismsPCI restores blood flow but does not stop atherosclerotic progression; long-term guideline-directed pharmacotherapy is used for secondary prevention. The study evaluates a Behavior Change Wheel–guided WeChat messaging program to support adherence.
Target PopulationPatients with coronary heart disease after PCI
Care SettingPost-PCI medication adherence support and secondary prevention; the study evaluated a 12-week WeChat messaging program.

Key Highlights

  • PCI can alleviate ischemic symptoms but does not prevent ongoing atherosclerotic progression or eliminate the risk of restenosis and recurrent cardiovascular events.
  • Guidelines cited in the article advise long-term, guideline-directed pharmacotherapy for secondary prevention after PCI.
  • Medication adherence after PCI is often inadequate; the article reports that adherence to dual antiplatelet therapy at 1 year is 50% to 70% in US and European registry data.
  • Mobile phone messaging is described as accessible and inexpensive, but prior post-PCI SMS intervention findings have been inconsistent.
  • The study evaluates a Behavior Change Wheel–guided WeChat messaging program over 12 weeks using a quasi-experimental design.

Guideline-Based Recommendations

Diagnosis

    Management

    • The article reports that current clinical guidelines advise long-term, guideline-directed pharmacotherapy for secondary prevention following PCI.
    • The study evaluates a 12-week Behavior Change Wheel–guided WeChat messaging program to enhance medication adherence; the provided article excerpt does not report its results.

    Monitoring & Follow-up

      Risks

      • The article identifies restenosis and recurrent cardiovascular events as ongoing risks after PCI; it reports restenosis in approximately 10% of cases.
      • Medication nonadherence is linked in the cited literature to greater cardiovascular risk.

      Patient & Prescribing Data

      Patients with coronary heart disease who have undergone PCI; the provided excerpt does not specify study eligibility criteria or sample characteristics.

      Long-term guideline-directed pharmacotherapy is advised after PCI. The study examines WeChat messaging as an adherence-support intervention over 12 weeks; intervention outcomes and medication-specific prescribing details are not included in the provided excerpt.

      Clinical Best Practices

      • Support long-term adherence to guideline-directed pharmacotherapy after PCI, as described in the article.
      • Consider the article’s identified adherence barriers, including financial constraints, structural barriers, and limited health literacy, when interpreting adherence challenges.
      • Do not assume that mobile messaging interventions consistently improve adherence; the article notes mixed findings from prior studies.

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