The article title links the imaging pattern to fat necrosis and dystrophic calcification; the supplied text does not provide further mechanistic findings.
Target Population
Adults with bilateral distal femoral metadiaphyseal sclerotic lesions on knee radiographs; the title identifies older women.
Care Setting
Retrospective imaging assessment at two Belgian institutions, including knee radiography, CT, MRI, and full-length lower-limb radiography.
Key Highlights
The described lesions are round or elongated, sometimes merging, and located in the distal femoral metadiaphysis.
Lesions were characterized radiographically as non-aggressive, without cortical erosion, periosteal reaction, or soft-tissue extension.
Patients with known skeletal disorders and several recognizable causes of sclerosis were excluded from the descriptive cohort.
The study compared clinical and laboratory parameters with those of 30 age- and sex-matched controls.
The supplied article text does not include study results, prevalence estimates, or detailed diagnostic and management recommendations.
Guideline-Based Recommendations
Diagnosis
Management
Monitoring & Follow-up
Risks
Patient & Prescribing Data
Retrospective cohort of adults with bilateral distal femoral metadiaphyseal sclerosis identified from knee radiographs at two Belgian institutions between 2018 and 2023; the article title describes the pattern in older women.
No treatment or prescribing data are provided in the supplied text.
A general-purpose AI model performed comparably to experienced readers, but substantial errors highlighted the limits of chest radiography for quantifying pleural fluid.
