Association of Low Prognostic Nutritional Index Score with Lymph Node Metastasis in Breast Cancer Patients, Unlike Hemoglobin-Albumin-Lymphocyte-Platelet Score - Scorecard - MDSpire
Advertisement
Association of Low Prognostic Nutritional Index Score with Lymph Node Metastasis in Breast Cancer Patients, Unlike Hemoglobin-Albumin-Lymphocyte-Platelet Score
Clinical Scorecard: Association of Low Prognostic Nutritional Index Score with Lymph Node Metastasis in Breast Cancer Patients, Unlike Hemoglobin-Albumin-Lymphocyte-Platelet Score
At a Glance
Category
Detail
Condition
Breast Cancer with Lymph Node Metastasis
Key Mechanisms
Nutritional status and immune function impact cancer progression and lymph node metastasis.
Target Population
Breast cancer patients, specifically those undergoing surgical intervention.
Care Setting
Oncology clinics and hospitals.
Key Highlights
Low PNI is associated with lymph node metastasis (LNM) in breast cancer patients.
HALP score did not show a significant association with LNM.
Median PNI levels were significantly lower in LNM-positive patients.
Optimal cutoff for PNI to predict LNM is 52.45.
Nutritional and immune interventions are recommended pre- and post-surgery.
Guideline-Based Recommendations
Diagnosis
Assess PNI and HALP scores in breast cancer patients to evaluate risk of LNM.
Management
Implement nutritional and immune interventions based on PNI levels.
Monitoring & Follow-up
Regularly monitor PNI and HALP scores during treatment.
Risks
Low PNI levels indicate increased risk of LNM and poor prognosis.
Patient & Prescribing Data
799 breast cancer patients with complete clinical data.
Focus on improving nutritional status to potentially reduce LNM risk.
Clinical Best Practices
Incorporate PNI assessment in preoperative evaluations.
Provide nutritional support to patients with low PNI scores.
Monitor immune function alongside nutritional status in cancer care.
