Development of Arthritis in a Large Real-World Cohort of Patients With Pediatric Onset Psoriasis - Scorecard - MDSpire

Development of Arthritis in a Large Real-World Cohort of Patients With Pediatric Onset Psoriasis

  • By

  • Malak Al-Gawahiri

  • Elke M. G. J. de Jong

  • Ellen J. H. Schatorjé

  • Esther P. A. H. Hoppenreijs

  • Juul M. P. A. van den Reek

  • Marieke M.B. Seyger

  • April 25, 2026

  • 0 min

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Clinical Scorecard: Incidence of Arthritis in a Large Cohort of Pediatric Patients Diagnosed with Psoriasis

At a Glance

CategoryDetail
ConditionPsoriatic Arthritis (PsA) in Pediatric Patients
Key MechanismsDevelopment of JPsA associated with psoriasis severity, age at diagnosis, and uveitis.
Target PopulationPediatric patients with psoriasis (<18 years) and young adults (≥18 years) with a history of psoriasis.
Care SettingDermatology and Pediatric Rheumatology

Key Highlights

  • 2% of children with psoriasis developed JPsA over a mean follow-up of 5 years.
  • Older age at psoriasis diagnosis and presence of uveitis are identified risk factors for JPsA.
  • JPsA accounts for approximately 8% of the Juvenile Idiopathic Arthritis population.
  • Diagnosis of JPsA is challenging, especially in patients without psoriatic lesions.

Guideline-Based Recommendations

Diagnosis

  • Children diagnosed with JPsA according to ILAR criteria.
  • Young adults diagnosed with PsA according to CASPAR criteria.

Management

  • Referral to a rheumatologist based on persistent joint complaints and elevated PEST scores.

Monitoring & Follow-up

  • Regular follow-up visits to assess PASI score, BSA, BMI, and nail involvement.

Risks

  • Risk factors for developing JPsA include older age at psoriasis diagnosis and uveitis.

Patient & Prescribing Data

Pediatric patients with plaque psoriasis followed into young adulthood.

Data collected on treatment history and clinical characteristics at baseline and follow-up.

Clinical Best Practices

  • Early diagnosis of psoriatic arthritis is crucial for prevention.
  • Consider referral to rheumatology for patients with persistent joint symptoms.

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