Case Report: Intravenous transplantation of autologous adipose tissue-derived mesenchymal stem cells attenuated atopic dermatitis
By
Kosuke Mabuchi
Yoshie Takahashi
Yuka Okinaka
Kana Nagase
Yosky Kataoka
Akihiko Taguchi
May 4, 2026
Clinical Scorecard: Case Study: Autologous Adipose Tissue-Derived Mesenchymal Stem Cell Infusion Reduced Symptoms of Atopic Dermatitis
At a Glance
Category Detail
Condition Atopic Dermatitis Key Mechanisms Gap junction-mediated reduction of vascular permeability and tissue inflammation. Target Population Patients with chronic pain and comorbid atopic dermatitis. Care Setting Clinical setting involving MSC transplantation.
Key Highlights
Significant improvement in atopic dermatitis symptoms post-MSC transplantation. Asthma attacks ceased following MSC treatment. Patient experienced relief from chronic itching and reduced steroid use. Increased serum levels of SDF1 and VEGF observed after MSC infusion. No recurrence of atopic dermatitis or asthma attacks during follow-up. Guideline-Based Recommendations
Diagnosis
Assess atopic dermatitis severity using Eczema Area and Severity Index. Management
Consider MSC transplantation for patients with refractory atopic dermatitis. Monitoring & Follow-up
Monitor serum levels of SDF1 and VEGF post-treatment. Risks
Potential for adverse effects related to MSC transplantation. Patient & Prescribing Data
32-year-old female with chronic lower back pain and atopic dermatitis.
Autologous MSC transplantation led to significant symptom relief and reduced medication use.
Clinical Best Practices
Evaluate patient history for exacerbating factors such as alcohol consumption. Follow up on symptom resolution and medication usage post-MSC treatment. References
