Case Report: Amiodarone-triggered refractory ventricular fibrillation storm in septic cardiomyopathy with pre-existing QT prolongation: termination using lidocaine and anisodamine - Scorecard - MDSpire
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Case Report: Amiodarone-triggered refractory ventricular fibrillation storm in septic cardiomyopathy with pre-existing QT prolongation: termination using lidocaine and anisodamine
Clinical Scorecard: Case Study: Refractory Ventricular Fibrillation Induced by Amiodarone in Septic Cardiomyopathy with Pre-existing QT Interval Prolongation: Successful Management with Lidocaine and Anisodamine
At a Glance
Category
Detail
Condition
Key Mechanisms
Reversible acute cardiac dysfunction caused by sepsis, exacerbated by QT-prolonging agents and systemic inflammatory responses.
Target Population
Care Setting
Key Highlights
Moxifloxacin and amiodarone can induce refractory TdP and VF in SCM, despite standard resuscitative measures.
Guideline-Based Recommendations
Diagnosis
Management
Discontinue QT-prolonging agents in cases of significant QTc prolongation.
Consider intravenous lidocaine and anisodamine for refractory TdP and VF.
Monitor renal function due to potential nephrotoxicity of medications used.
Monitoring & Follow-up
Risks
Patient & Prescribing Data
Elderly patients (aged 65 and older) with septic shock and cardiac dysfunction.
Clinical Best Practices
Immediate recognition and treatment of TdP to prevent progression to VF.
Utilize continuous cardiac monitoring in patients with septic cardiomyopathy.
Consider magnesium administration in the management of TdP.
