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Development and evaluation of a preliminary risk assessment model for psychological distress among patients with brain tumors: a cross-sectional analysis

  • By

  • Ying Li

  • Yuyu Duan

  • Yangmei Su

  • Zhiman Zheng

  • Dongqi Zou

  • Zhihuan Zhou

  • January 22, 2026

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Clinical Scorecard: Development and evaluation of a preliminary risk assessment model for psychological distress among patients with brain tumors: a cross-sectional analysis

At a Glance

CategoryDetail
ConditionPsychological distress in brain tumor patients
Key MechanismsFinancial toxicity, self-efficacy, medical coping strategies
Target PopulationPatients with histopathologically confirmed brain tumors aged 18-80
Care SettingNeuro-oncology Department, Sun Yat-sen University Cancer Center

Key Highlights

  • 44.5% to 76.0% of brain tumor patients experience clinically significant psychological distress.
  • Financial toxicity significantly correlates with psychological distress.
  • Self-efficacy inversely relates to psychological distress.
  • Adaptive coping strategies can mitigate psychological distress.
  • Early screening for psychological distress is crucial for intervention.

Guideline-Based Recommendations

Diagnosis

  • Implement early screening for psychological distress in brain tumor patients.

Management

  • Develop targeted psychosocial care programs based on identified risk factors.

Monitoring & Follow-up

  • Regularly assess psychological distress and self-efficacy in patients.

Risks

  • Consider financial toxicity as a significant risk factor for psychological distress.

Patient & Prescribing Data

321 brain tumor patients recruited from a single center.

Financial strain and low self-efficacy are critical factors influencing psychological distress.

Clinical Best Practices

  • Utilize adaptive coping strategies to enhance patient quality of life.
  • Encourage patient participation in medical decision-making to improve self-efficacy.
  • Address financial toxicity in treatment planning and support.

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