The association of remnant cholesterol inflammatory index with the risk of major adverse cardiovascular events in patients with angina undergoing percutaneous coronary intervention: a retrospective study - Scorecard - MDSpire

The association of remnant cholesterol inflammatory index with the risk of major adverse cardiovascular events in patients with angina undergoing percutaneous coronary intervention: a retrospective study

  • By

  • Yazhao Sun

  • Xiao Yu

  • Chunlan Bai

  • Dongsheng Liu

  • Wenrui Xiong

  • June 17, 2026

  • 0 min

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Clinical Scorecard: Linking the Remnant Cholesterol-Inflammation Index to Major Adverse Cardiovascular Event Risk in Angina Patients Undergoing Percutaneous Coronary Intervention: A Retrospective Analysis

At a Glance

CategoryDetail
ConditionAngina and Major Adverse Cardiovascular Events (MACE)
Key MechanismsRemnant cholesterol (RC) and high-sensitivity C-reactive protein (hs-CRP) reflect metabolic and inflammatory risks.
Target PopulationPatients with angina undergoing percutaneous coronary intervention (PCI)
Care SettingCardiology

Key Highlights

  • Study included 2,171 angina patients with a median follow-up of 36 months.
  • Each standard deviation increase in RCII was associated with a 5% higher MACE risk.
  • Moderate discriminatory ability of RCII for MACE risk was demonstrated with AUCs ranging from 0.739 to 0.786 over 30 months.
  • RCII significantly associated with MACE risk across various subgroups including age, sex, and comorbidities.
  • RCII may serve as a potential clinical biomarker for assessing MACE risk.

Guideline-Based Recommendations

Diagnosis

  • Evaluate baseline RCII in patients with angina undergoing PCI.

Management

  • Consider RCII as a potential biomarker for cardiovascular risk assessment.

Monitoring & Follow-up

  • Monitor RCII levels to evaluate ongoing cardiovascular risk.

Risks

  • Patients with elevated RCII may have increased risk of MACE.

Patient & Prescribing Data

Angina patients undergoing PCI.

Focus on managing both dyslipidemia and inflammation to reduce MACE risk.

Clinical Best Practices

  • Incorporate RCII measurement in routine risk assessment for angina patients.
  • Address both metabolic and inflammatory factors in cardiovascular risk management.

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