Case Report: Pembrolizumab unmasks a capillary leak syndrome with chylothorax in early TNBC - Scorecard - MDSpire

Case Report: Pembrolizumab unmasks a capillary leak syndrome with chylothorax in early TNBC

  • By

  • Naïla Benkalfate

  • Ghazi Hadjamara

  • Caroline Petorin

  • Magaly Zappa

  • Aimable Habonimana

  • Dufens Pierre Louis

  • Anne-Laure Chene

  • Jean-Patrick Clarke

  • Renan Liberge

  • Kinane Drak Alsibai

  • Claire Defrance

  • Barbara Pistilli

  • Baptiste Boulet

  • Soraya Benguerfi

  • Houari Aissaoui

  • May 22, 2026

  • 0 min

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Clinical Scorecard: Case Study: Pembrolizumab Reveals Capillary Leak Syndrome Accompanied by Chylothorax in Early Triple-Negative Breast Cancer

At a Glance

CategoryDetail
Condition
Key MechanismsVascular and lymphatic endothelial dysfunction (ensure direct sourcing).
Target Population
Care Setting

Key Highlights

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Guideline-Based Recommendations

Diagnosis

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Management

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Monitoring & Follow-up

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Risks

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Patient & Prescribing Data

Female, 40 years old, diagnosed with early-stage TNBC.

Pembrolizumab was resumed after neoadjuvant chemotherapy and led to CLS.

Clinical Best Practices

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Related Resources & Content

Original Source(s)

Case Report: Pembrolizumab unmasks a capillary leak syndrome with chylothorax in early TNBC

  • by Naïla Benkalfate, Ghazi Hadjamara, Caroline Petorin, Magaly Zappa, Aimable Habonimana, Dufens Pierre Louis, Anne-Laure Chene, Jean-Patrick Clarke, Renan Liberge, Kinane Drak Alsibai, Claire Defrance, Barbara Pistilli, Baptiste Boulet, Soraya Benguerfi, Houari Aissaoui

  • May 22, 2026

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