Depression after aneurysmal subarachnoid hemorrhage: development of a screening tool and discharge user interface
By
Stefan W. Koester
Brandon K. Hoglund
Joelle N. Hartke
Robert F. Rudy
Ashutosh P. Jadhav
Andrew F. Ducruet
Felipe C. Albuquerque
Joshua S. Catapano
Laura A. Snyder
Michael T. Lawton
June 24, 2025
Clinical Scorecard: Post-Aneurysmal Subarachnoid Hemorrhage Depression: Creation of a Screening Instrument and Discharge Interface
At a Glance
Category Detail
Condition Post-aneurysmal subarachnoid hemorrhage (aSAH) depression
Key Mechanisms Psychological sequelae following aSAH including anxiety and depression linked to clinical and demographic risk factors
Target Population Patients treated for aSAH with mRS ≤ 3 at follow-up and able to cooperate with depression screening
Care Setting Neurological inpatient and outpatient follow-up care, discharge counseling
Key Highlights
Approximately 29.6% of patients post-aSAH screened positive for chronic depression. A simplified 5-point scoring system was developed using tobacco use, COPD, diabetes, and other factors to stratify depression risk. An interactive mobile application was created for discharge staff to assess depression risk and provide patient-specific counseling.
Guideline-Based Recommendations
Diagnosis
Use a screening questionnaire based on SIGECAPS criteria with ≥5 positive responses indicating chronic depression. Assess risk factors including tobacco use, COPD, diabetes, aneurysm characteristics, and discharge mRS score.
Management
Implement patient-specific discharge counseling based on risk stratification from the 5-point scoring system. Provide patients with resources and follow-up plans via QR code linked to the mobile application.
Monitoring & Follow-up
Conduct long-term follow-up depression screening in patients treated for aSAH. Monitor neurological and psychiatric sequelae during outpatient visits.
Risks
Recognize that tobacco use and COPD significantly increase risk of post-aSAH depression. Consider comorbidities and aneurysm-related complications as contributors to depression risk.
Patient & Prescribing Data
Patients with aneurysmal subarachnoid hemorrhage treated via endovascular or microsurgical methods
Risk stratification enables targeted counseling to potentially reduce incidence of post-aSAH depression and improve quality of life
Clinical Best Practices
Screen all eligible aSAH survivors for depression using validated questionnaires during follow-up. Utilize the 5-point scoring system to identify patients at low, medium, and high risk for chronic depression. Incorporate the mobile application into discharge procedures to facilitate risk communication and resource provision. Address modifiable risk factors such as tobacco use during discharge counseling. Ensure multidisciplinary follow-up including neurological and psychiatric evaluation.
References