Rapid progression from croup to complete lung collapse: a case report of central airway obstruction by mucopurulent cast in influenza A (H3N2) and Pseudomonas aeruginosa coinfection in a toddler - Scorecard - MDSpire

Rapid progression from croup to complete lung collapse: a case report of central airway obstruction by mucopurulent cast in influenza A (H3N2) and Pseudomonas aeruginosa coinfection in a toddler

  • By

  • Xiumin Zhang

  • Fujing Xie

  • Jingcai Wang

  • Jing Zhao

  • Cuicui Guo

  • June 2, 2026

  • 0 min

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Clinical Scorecard: Acute Deterioration from Croup to Total Lung Collapse: A Case Study of Central Airway Obstruction Due to Mucopurulent Cast in a Toddler with Influenza A (H3N2) and Pseudomonas aeruginosa Coinfection

At a Glance

CategoryDetail
Condition
Key MechanismsViral-induced subglottic edema leading to airway obstruction and secondary bacterial infection.
Target Population
Care Setting

Key Highlights

  • Croup is commonly caused by viral infections, with severe cases potentially leading to airway obstruction.
  • Co-infection with Pseudomonas aeruginosa can complicate influenza A infections, resulting in severe respiratory distress.
  • Mucopurulent casts can lead to total lung collapse in rare cases.
  • Rapid clinical deterioration may occur despite glucocorticoid therapy.
  • Bronchoscopy can be necessary for diagnosis and treatment of airway obstruction.

Guideline-Based Recommendations

Diagnosis

  • Consider bacterial tracheitis in cases of rapid clinical deterioration or poor response to treatment.

Management

  • Use glucocorticoids for initial management of croup.
  • Administer sensitive antibiotics for bacterial co-infections.

Monitoring & Follow-up

  • Monitor vital signs and respiratory status closely in patients with severe croup.

Risks

  • Risk of respiratory failure and total lung collapse due to airway obstruction.

Patient & Prescribing Data

Use of dexamethasone and sensitive antibiotics, along with peramivir for viral infection.

Clinical Best Practices

  • Perform bronchoscopy in cases of suspected airway obstruction due to mucopurulent casts.
  • Ensure timely intervention in cases of acute respiratory distress.

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