Regional disparities and hospital performance patterns in acute stroke reperfusion: a multicenter study in Sichuan Province, China
By
Shu Liu
Rong Li
Yan Liu
Haitao Zhang
Rong Hu
Guangyu Zhong
Hua Liu
July 1, 2026
Clinical Scorecard: Hospital Performance and Geographic Variations in Acute Stroke Reperfusion: A Multicenter Analysis from Sichuan Province, China
At a Glance
Category Detail
Condition Acute Ischemic Stroke (AIS)
Key Mechanisms Timely reperfusion therapy including intravenous thrombolysis (IVT) and endovascular thrombectomy (EVT)
Target Population Patients diagnosed with AIS in Chengdu, Sichuan Province
Care Setting Multicenter hospitals in Chengdu
Key Highlights
High and stable door-to-needle time (DNT) and IVT rates observed. Notable variation in puncture-to-recanalization time (PRT) compliance and EVT accessibility. Tertiary A-level hospitals and certified stroke centers showed higher performance in key indicators. Transient spike in EVT-related mortality in non-tertiary A-level and non-stroke center hospitals in 2023. Identified three hospital-level performance patterns indicating disparities in stroke care.
Guideline-Based Recommendations
Diagnosis
Diagnosis of AIS based on clinical symptoms and neuroimaging findings.
Management
IVT within 4.5 hours and EVT within 6 hours for eligible patients.
Monitoring & Follow-up
Monitor door-to-needle time (DNT), door-to-puncture time (DPT), and puncture-to-recanalization time (PRT).
Risks
Increased EVT-related mortality in non-tertiary A-level and non-stroke center hospitals.
Patient & Prescribing Data
Patients with acute ischemic stroke treated in Chengdu hospitals.
Timely reperfusion therapy is critical for improving outcomes.
Clinical Best Practices
Implement hierarchical stroke center networks to improve access and quality of care. Enhance training and infrastructure in non-tertiary A-level hospitals.
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