Bubble-test for detection of a patent foramen ovale in young to middle-aged ischemic stroke patients - Scorecard - MDSpire

Bubble-test for detection of a patent foramen ovale in young to middle-aged ischemic stroke patients

  • By

  • Anna Bogdanova

  • Lena Mers

  • Alexander Sekita

  • Laura Besendorf

  • Ludwig Singer

  • Tobias Engelhorn

  • Caroline Merkel

  • Kosmas Macha

  • Arnd Doerfler

  • Stefan Schwab

  • Stefan T. Gerner

  • May 11, 2026

  • 0 min

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Clinical Scorecard: Transcranial Doppler Bubble Test for Identifying Patent Foramen Ovale in Younger Adults with Ischemic Stroke

At a Glance

CategoryDetail
Condition
Key Mechanisms
Target PopulationPatients aged ≤65 years with acute ischemic stroke of unknown origin
Care Setting

Key Highlights

  • Add specificity for sensitivity and specificity values.

Guideline-Based Recommendations

Diagnosis

    Management

    • Confirm positive TCD-bubble results with transesophageal echocardiography (TEE) as a confirmatory test.

    Monitoring & Follow-up

      Risks

        Patient & Prescribing Data

        Younger adults aged ≤65 years with cryptogenic ischemic stroke.

        Clinical Best Practices

        • Include details on patient stability criteria for TCD-bubble assessment.

        Related Resources & Content

        Original Source(s)

        Bubble-test for detection of a patent foramen ovale in young to middle-aged ischemic stroke patients

        • by Anna Bogdanova, Lena Mers, Alexander Sekita, Laura Besendorf, Ludwig Singer, Tobias Engelhorn, Caroline Merkel, Kosmas Macha, Arnd Doerfler, Stefan Schwab, Stefan T. Gerner

        • May 11, 2026

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