Systemic Immune Responses in Patients with Spine Surgery Related Infections - Scorecard - MDSpire

Systemic Immune Responses in Patients with Spine Surgery Related Infections

  • By

  • Fehrenbach, Pia

  • Lang, Siegmund

  • Gocević, Maja

  • Kwant, Puk

  • Haschtmann, Daniel

  • Fekete, Tamas F.

  • Menzel, Ursula

  • De Jong, Esther Christina

  • Moriarty, Fintan Thomas

  • Grad, Sibylle

  • Loibl, Markus

  • May 4, 2026

  • 0 min

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Clinical Scorecard: Immune System Reactions in Patients Experiencing Infections Following Spine Surgery

At a Glance

CategoryDetail
Condition
Key MechanismsAltered immune cell profiles in patients with infections (source needed)
Target Population
Care Setting

Key Highlights

  • Significant differences in immune cell profiles between infection and non-infection groups (source needed)
  • Decreased natural killer cells and monocytes in infection patients (source needed)
  • Increased Th17 and HLA-DR+ CD4+ T cells in infection patients (source needed)

Guideline-Based Recommendations

Diagnosis

  • Use of immune cell profiles for differentiating between infection and non-infection (source needed)

Management

  • Further research into immune activation and exhaustion for therapeutic strategies (source needed)

Monitoring & Follow-up

  • Monitoring immune cell counts post-surgery may aid in early detection of SSIs (source needed)

Risks

  • Increased risk of SSIs associated with altered immune responses (source needed)

Patient & Prescribing Data

Patients who underwent spine surgery and developed infections

Understanding immune responses may inform future therapeutic options

Clinical Best Practices

  • Consider immune profiling in patients at risk for SSIs (source needed)
  • Monitor changes in immune cell populations post-surgery (source needed)

Related Resources & Content

    Original Source(s)

    Systemic Immune Responses in Patients with Spine Surgery Related Infections

    • by Fehrenbach, Pia , Lang, Siegmund , Gocević, Maja , Kwant, Puk , Haschtmann, Daniel , Fekete, Tamas F., Menzel, Ursula , De Jong, Esther Christina, Moriarty, Fintan Thomas, Grad, Sibylle , Loibl, Markus

    • May 4, 2026

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