Work Reintegration Following Low-Grade Glioma Treatment: Evaluating Return Rates and Identifying Patient Challenges
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By
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Jasmine C. Kennedy
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Stephen J. Price
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Tom Manly
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Emma Woodberry
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Mary Burton
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April 21, 2026
Clinical Scorecard: Work Reintegration Following Low-Grade Glioma Treatment: Evaluating Return Rates and Identifying Patient Challenges
At a Glance
| Category | Detail |
|---|
| Condition | Low-Grade Glioma (LGG) |
| Key Mechanisms | Mutated glial cells (astrocytes and oligodendrocytes), IDH gene mutation, and 1p/19q codeletion. |
| Target Population | Adults aged 18-66 diagnosed with low-grade glioma. |
| Care Setting | Oncology and neuropsychological rehabilitation. |
Key Highlights
- 52% of LGG patients return to work 1 year post-surgery; 63% by year 2.
- Executive functions are not returning to baseline levels after LGG surgery.
- Cognitive impairment risks include effects from the tumour, surgery, and treatment.
- Lack of formal cognitive screening methods for LGG patients post-surgery.
- Vocational rehabilitation is not standard practice in LGG treatment.
Guideline-Based Recommendations
Diagnosis
- Assess cognitive function, particularly executive functions, post-surgery.
Management
- Implement cognitive and vocational rehabilitation strategies.
Monitoring & Follow-up
- Regularly evaluate cognitive functioning and return-to-work outcomes.
Risks
- Monitor for cognitive impairments that may hinder return to work.
Patient & Prescribing Data
Adults aged 18-66 with low-grade glioma.
Focus on preserving quality of life and supporting return to work.
Clinical Best Practices
- Enhance communication between employers and employees regarding return-to-work options.
- Incorporate cognitive rehabilitation into treatment plans for LGG patients.
- Utilize qualitative assessments to understand patient challenges in returning to work.
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