Work Reintegration Following Low-Grade Glioma Treatment: Evaluating Return Rates and Identifying Patient Challenges
By
Jasmine C. Kennedy
Stephen J. Price
Tom Manly
Emma Woodberry
Mary Burton
April 21, 2026
Clinical Scorecard: Work Reintegration Following Low-Grade Glioma Treatment: Evaluating Return Rates and Identifying Patient Challenges
At a Glance
Category Detail
Condition Low-Grade Glioma (LGG)
Key Mechanisms Mutated glial cells (astrocytes and oligodendrocytes), IDH gene mutation, and 1p/19q codeletion.
Target Population Adults aged 18-66 diagnosed with low-grade glioma.
Care Setting Oncology and neuropsychological rehabilitation.
Key Highlights
52% of LGG patients return to work 1 year post-surgery; 63% by year 2. Executive functions are not returning to baseline levels after LGG surgery. Cognitive impairment risks include effects from the tumour, surgery, and treatment. Lack of formal cognitive screening methods for LGG patients post-surgery. Vocational rehabilitation is not standard practice in LGG treatment.
Guideline-Based Recommendations
Diagnosis
Assess cognitive function, particularly executive functions, post-surgery.
Management
Implement cognitive and vocational rehabilitation strategies.
Monitoring & Follow-up
Regularly evaluate cognitive functioning and return-to-work outcomes.
Risks
Monitor for cognitive impairments that may hinder return to work.
Patient & Prescribing Data
Adults aged 18-66 with low-grade glioma.
Focus on preserving quality of life and supporting return to work.
Clinical Best Practices
Enhance communication between employers and employees regarding return-to-work options. Incorporate cognitive rehabilitation into treatment plans for LGG patients. Utilize qualitative assessments to understand patient challenges in returning to work.
References